尼日利亚非充气式抗休克裤治疗产科出血的对比研究。
A comparative study of the non-pneumatic anti-shock garment for the treatment of obstetric hemorrhage in Nigeria.
机构信息
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California 94105, USA.
出版信息
Int J Gynaecol Obstet. 2009 Nov;107(2):121-5. doi: 10.1016/j.ijgo.2009.06.005. Epub 2009 Jul 22.
OBJECTIVE
To determine whether the non-pneumatic anti-shock garment (NASG) can improve maternal outcome.
METHODS
Women were enrolled in a pre-intervention phase (n=83) and an intervention phase (n=86) at a referral facility in Katsina, Nigeria, from November 2006 to November 2007. Entry criteria were obstetric hemorrhage (>or=750 mL) and a clinical sign of shock (systolic blood pressure <100 mm Hg or pulse >100 beats per minute). To determine differences in demographics, condition on study entry, treatment, and outcome, t tests and chi(2) tests were used. Relative risk (RR) and 95% confidence interval (CI) were estimated for the primary outcome, mortality.
RESULTS
Mean measured blood loss in the intervention phase was 73.5+/-93.9 mL, compared with 340.4+/-248.2 mL pre-intervention (P<0.001). Maternal mortality was lower in the intervention phase than in the pre-intervention phase (7 [8.1%]) vs 21 [25.3%]) (RR 0.32; 95% CI, 0.14-0.72).
CONCLUSION
The NASG showed potential for reducing blood loss and maternal mortality caused by obstetric hemorrhage-related shock.
目的
确定非充气式抗休克服（NASG）能否改善产妇结局。
方法
2006 年 11 月至 2007 年 11 月，在尼日利亚卡齐纳的一家转诊医院，对纳入的妇女进行了干预前阶段（n=83）和干预阶段（n=86）的研究。纳入标准为产科出血（>750 mL）和休克的临床体征（收缩压<100 mmHg 或脉搏>100 次/分钟）。为了确定在人口统计学、研究开始时的状况、治疗和结局方面的差异，采用 t 检验和卡方检验。主要结局（死亡率）的相对风险（RR）和 95%置信区间（CI）是通过计算得到的。
结果
干预阶段的平均测量出血量为 73.5+/-93.9 mL，而干预前阶段为 340.4+/-248.2 mL（P<0.001）。干预阶段的产妇死亡率低于干预前阶段（7 [8.1%]）与 21 [25.3%]）（RR 0.32；95% CI，0.14-0.72）。
结论
非充气式抗休克服在减少产科出血相关性休克引起的失血量和产妇死亡率方面具有潜力。
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