Njau J D, Goodman C, Kachur S P, Palmer N, Khatib R A, Abdulla S, Mills A, Bloland P
Ifakara Health Research and Development Center, Ifakara, Tanzania.
Trop Med Int Health. 2006 Mar;11(3):299-313. doi: 10.1111/j.1365-3156.2006.01569.x.
To investigate the variation in malaria parasitaemia, reported fever, care seeking, antimalarials obtained and household expenditure by socio-economic status (SES), and to assess the implications for ensuring equitable and appropriate use of antimalarial combination therapy.
A total of 2,500 households were surveyed in three rural districts in southern Tanzania in mid-2001. Blood samples and data on SES were collected from all households. Half the households completed a detailed questionnaire on care seeking and treatment costs. Households were categorised into SES thirds based on an index of household wealth derived using principal components analysis.
Of individuals completing the detailed survey, 16% reported a fever episode in the previous 2 weeks. People from the better-off stratum were significantly less likely to be parasitaemic, and significantly more likely to obtain antimalarials than those in the middle or poor stratum. The better treatment obtained by the better off led them to spend two to three times more than the middle and poor third spent. This reflected greater use of non-governmental organisation (NGO) facilities, which were the most expensive source of care, and higher expenditure at NGO facilities and drug stores.
The coverage of appropriate malaria treatment was low in all SES groups, but the two poorer groups were particularly disadvantaged. As countries switch to antimalarial combination therapy, distribution must be targeted to ensure that the poorest groups fully benefit from these new and highly effective medicines.
调查按社会经济地位(SES)划分的疟疾寄生虫血症、报告的发热情况、寻求治疗情况、获得的抗疟药以及家庭支出的变化,并评估确保公平且恰当地使用抗疟联合疗法的影响因素。
2001年年中,在坦桑尼亚南部的三个农村地区对总共2500户家庭进行了调查。从所有家庭收集了血样和社会经济地位数据。一半的家庭完成了一份关于寻求治疗和治疗费用的详细问卷。根据使用主成分分析得出的家庭财富指数,将家庭分为社会经济地位三等份。
在完成详细调查的个体中,16%报告在过去2周内有发热发作。富裕阶层的人寄生虫血症的可能性显著较低,且获得抗疟药的可能性显著高于中等或贫困阶层。富裕阶层获得的更好治疗使他们的花费比中等和贫困三等份人群多两到三倍。这反映出他们更多地使用非政府组织(NGO)设施,而这些设施是最昂贵的治疗来源,并且在非政府组织设施和药店的支出更高。
在所有社会经济地位群体中,适当的疟疾治疗覆盖率都很低,但两个较贫困群体尤其处于不利地位。随着各国转向抗疟联合疗法,必须有针对性地进行分发,以确保最贫困群体能充分受益于这些新型高效药物。