Marquis Vincent L, Dao Thuan, Farzaneh Mahsa, Abitbol Sarah, Friedman Shimon
MSc Program in Endodontics, Department of Graduate Endodontics, University of Toronto, Toronto, Ontario, Canada.
J Endod. 2006 Apr;32(4):299-306. doi: 10.1016/j.joen.2005.10.050.
The 4- to 6-year outcome of initial endodontic treatment was assessed for phase III (1998-1999) of the Toronto Study. Of the 532 teeth treated, 248 were from discontinuers (excluded), 142 from dropouts, 10 extracted, and 132 (50% recall) examined for outcome: healed (no apical periodontitis [AP], signs, symptoms) or diseased. Phase III was analyzed alone and combined with phases I, II (n = 373 teeth). Logistic regression performed on the combined phases I-III sample identified significant (p < or = 0.05) outcome predictors: preoperative AP (OR = 3.5; CI 1.7-7.2; healed: absent, 93%; present, 80%), number of roots (OR = 2.2; CI 1.0-4.7; healed: 1 - 92%; > or =2 - 83%), and intraoperative complications (OR = 2.2; CI 1.1-4.5; healed: absent, 88%; present, 76%). Treatment technique (OR = 2.8; CI 1.3-6.1; healed: Schilder, 89%; alternative, 73%) was suggested as an outcome predictor in teeth with AP, requiring confirmation from randomized controlled trials.
对多伦多研究第三阶段（1998 - 1999年）初始牙髓治疗的4至6年结果进行了评估。在接受治疗的532颗牙齿中，248颗来自治疗中断者（排除），142颗来自退出者，10颗被拔除，132颗（50%回访）接受了结果检查：愈合（无根尖周炎[AP]、体征、症状）或患病。第三阶段单独进行分析，并与第一、二阶段（n = 373颗牙齿）合并分析。对第一至三阶段合并样本进行的逻辑回归分析确定了显著（p≤0.05）的结果预测因素：术前AP（比值比[OR]=3.5；可信区间[CI]1.7 - 7.2；愈合：无，93%；有，80%）、牙根数量（OR = 2.2；CI 1.0 - 4.7；愈合：1个 - 92%；≥2个 - 83%）和术中并发症（OR = 2.2；CI 1.1 - 4.5；愈合：无，88%；有，76%）。治疗技术（OR = 2.8；CI 1.3 - 6.1；愈合：Schilder法，89%；其他方法，73%）被认为是患有AP牙齿的结果预测因素，需要随机对照试验予以证实。
