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无症状淋病的流行病学关联因素

Epidemiological correlates of asymptomatic gonorrhea.

作者信息

Bozicevic Ivana, Fenton Kevin A, Martin Iona M C, Rudd Elizabeth A, Ison Catharine A, Nanchahal Kiran, Wellings Kaye

机构信息

Public and Environmental Health Research Unit, London School of Hygiene and Tropical Medicine, London, UK.

出版信息

Sex Transm Dis. 2006 May;33(5):289-95. doi: 10.1097/01.olq.0000194582.44222.c9.

DOI:10.1097/01.olq.0000194582.44222.c9
PMID:16554697
Abstract

OBJECTIVES

To assess correlates of asymptomatic gonorrhea among patients attending Genitourinary Medicine Clinics participating in the Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP) in England for 2001-2003.

STUDY DESIGN

GRASP is a sentinel surveillance program that monitors antimicrobial resistance to Neisseria gonorrhoeae. Data collection occurs annually in June to August each year.

RESULTS

Women with previously diagnosed gonorrhea had decreased odds of asymptomatic gonococcal infection, as did women diagnosed with other sexually transmitted infections (all except chlamydia, syphilis, herpes, and warts). Heterosexual men, but not women, coinfected with chlamydia had significantly higher likelihood of being diagnosed with asymptomatic gonorrhea, as did homosexual men coinfected with syphilis and warts.

CONCLUSION

The heterogeneity in correlates of asymptomatic gonorrhea has implications for screening in clinical settings. Such findings also depend on the extent of testing on sexually transmitted infections from different sites of infection, which has particular relevance in homosexual men and would thus need to be investigated in other studies.

摘要

目的

评估2001 - 2003年在英格兰参加淋病抗菌药物耐药监测项目(GRASP)的泌尿生殖医学诊所就诊的患者中无症状淋病的相关因素。

研究设计

GRASP是一个监测淋病奈瑟菌对抗菌药物耐药性的哨点监测项目。每年6月至8月进行数据收集。

结果

既往诊断有淋病的女性无症状淋病感染几率降低,诊断有其他性传播感染(除衣原体、梅毒、疱疹和疣之外的所有感染)的女性也是如此。感染衣原体的异性恋男性(而非女性)被诊断为无症状淋病的可能性显著更高,感染梅毒和疣的男同性恋者也是如此。

结论

无症状淋病相关因素中的异质性对临床筛查有影响。这些发现还取决于对来自不同感染部位的性传播感染的检测范围,这在男同性恋者中尤为相关,因此需要在其他研究中进行调查。

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