Osuna R, Bender R A
Department of Biology, University of Michigan, Ann Arbor 48109-1048.
J Bacteriol. 1991 Oct;173(20):6626-31. doi: 10.1128/jb.173.20.6626-6631.1991.
The catabolite gene activator protein from Klebsiella aerogenes (CAPK) and the corresponding protein from Escherichia coli (CAPE) were shown to be nearly identical. Both CAPK and CAPE activated transcription from the CAP-dependent promoters derived from E. coli and K. aerogenes. The crp gene from K. aerogenes (encoding CAP) is tightly linked to rpsL. The nucleotide sequence of crp predicts an amino acid sequence for CAPK that differs in only one position from that of CAPE.
产气克雷伯菌的分解代谢基因激活蛋白(CAPK)和大肠杆菌的相应蛋白(CAPE)被证明几乎完全相同。CAPK和CAPE都能激活源自大肠杆菌和产气克雷伯菌的CAP依赖性启动子的转录。产气克雷伯菌的crp基因(编码CAP)与rpsL紧密连锁。crp的核苷酸序列预测的CAPK氨基酸序列与CAPE的氨基酸序列仅在一个位置上有所不同。