• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Sliding into home: facilitated p53 search for targets by the basic DNA binding domain.

作者信息

Liu Y, Kulesz-Martin M F

机构信息

Department of Dermatology, Oregon Health & Science University, Portland 97239, USA.

出版信息

Cell Death Differ. 2006 Jun;13(6):881-4. doi: 10.1038/sj.cdd.4401905.

DOI:10.1038/sj.cdd.4401905
PMID:16557271
Abstract
摘要

相似文献

1
Sliding into home: facilitated p53 search for targets by the basic DNA binding domain.滑向“本垒”:p53的碱性DNA结合结构域助力其寻找靶标
Cell Death Differ. 2006 Jun;13(6):881-4. doi: 10.1038/sj.cdd.4401905.
2
The versatile interactions of p53 with DNA: when flexibility serves specificity.p53与DNA的多样相互作用:灵活性服务于特异性之时。
Cell Death Differ. 2006 Jun;13(6):885-9. doi: 10.1038/sj.cdd.4401909.
3
Modulation of the cyclin-dependent kinase inhibitor p21(WAF1/Cip1) gene by Zac1 through the antagonistic regulators p53 and histone deacetylase 1 in HeLa Cells.在HeLa细胞中,Zac1通过拮抗调节因子p53和组蛋白去乙酰化酶1对细胞周期蛋白依赖性激酶抑制剂p21(WAF1/Cip1)基因进行调控。
Mol Cancer Res. 2008 Jul;6(7):1204-14. doi: 10.1158/1541-7786.MCR-08-0123.
4
Translational research? Ribosome integrity and a new p53 tumor suppressor checkpoint.转化研究?核糖体完整性与一种新的p53肿瘤抑制检查点。
Cell Death Differ. 2006 Jun;13(6):898-901. doi: 10.1038/sj.cdd.4401923.
5
LKB1 is recruited to the p21/WAF1 promoter by p53 to mediate transcriptional activation.LKB1被p53招募至p21/WAF1启动子,以介导转录激活。
Cancer Res. 2006 Nov 15;66(22):10701-8. doi: 10.1158/0008-5472.CAN-06-0999.
6
A single recombinant adenovirus expressing p53 and p21-targeting artificial microRNAs efficiently induces apoptosis in human cancer cells.一种表达靶向p53和p21的人工微小RNA的重组腺病毒可有效诱导人癌细胞凋亡。
Clin Cancer Res. 2009 Jun 1;15(11):3725-32. doi: 10.1158/1078-0432.CCR-08-2396. Epub 2009 May 19.
7
Transcriptional activation of p53 by Pitx1.Pitx1对p53的转录激活作用。
Cell Death Differ. 2007 Nov;14(11):1893-907. doi: 10.1038/sj.cdd.4402209. Epub 2007 Aug 31.
8
Transcriptional regulation by p53: one protein, many possibilities.p53介导的转录调控:一种蛋白,多种可能。
Cell Death Differ. 2006 Jun;13(6):951-61. doi: 10.1038/sj.cdd.4401916.
9
A novel antioxidant 3-O-Caffeoyl-1-methylquinic acid enhances ultraviolet A-mediated apoptosis in immortalized HaCaT keratinocytes via Sp1-dependent transcriptional activation of p21(WAF1/Cip1).一种新型抗氧化剂3-O-咖啡酰-1-甲基奎尼酸通过Sp1依赖的p21(WAF1/Cip1)转录激活增强紫外线A介导的永生化HaCaT角质形成细胞凋亡。
Oncogene. 2007 May 24;26(24):3559-71. doi: 10.1038/sj.onc.1210135. Epub 2006 Dec 4.
10
The maintenance of hippocampal pyramidal neuron populations is dependent on the modulation of specific cell cycle regulators by thyroid hormones.海马锥体神经元群体的维持依赖于甲状腺激素对特定细胞周期调节因子的调控。
Brain Res. 2009 May 19;1271:27-35. doi: 10.1016/j.brainres.2009.02.043. Epub 2009 Mar 6.

引用本文的文献

1
Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity.p53 快速募集到 DNA 损伤位点指导 DNA 修复选择和完整性。
Proc Natl Acad Sci U S A. 2022 Mar 8;119(10):e2113233119. doi: 10.1073/pnas.2113233119. Epub 2022 Mar 2.
2
Circular RNA CDR1as disrupts the p53/MDM2 complex to inhibit Gliomagenesis.环状 RNA CDR1as 破坏 p53/MDM2 复合物抑制Gliomagenesis。
Mol Cancer. 2020 Sep 7;19(1):138. doi: 10.1186/s12943-020-01253-y.
3
The RNF20/40 complex regulates p53-dependent gene transcription and mRNA splicing.
RNF20/40 复合物调节 p53 依赖性基因转录和 mRNA 剪接。
J Mol Cell Biol. 2020 Feb 20;12(2):113-124. doi: 10.1093/jmcb/mjz045.
4
ROCK inhibitor reduces Myc-induced apoptosis and mediates immortalization of human keratinocytes.ROCK抑制剂可减少Myc诱导的细胞凋亡,并介导人角质形成细胞的永生化。
Oncotarget. 2016 Oct 11;7(41):66740-66753. doi: 10.18632/oncotarget.11458.
5
p53 at a glance.p53 一览。
J Cell Sci. 2010 Aug 1;123(Pt 15):2527-32. doi: 10.1242/jcs.064501.
6
Transcriptional regulation by p53.p53 的转录调控。
Cold Spring Harb Perspect Biol. 2010 Aug;2(8):a000935. doi: 10.1101/cshperspect.a000935. Epub 2010 Apr 28.
7
Preferred drifting along the DNA major groove and cooperative anchoring of the p53 core domain: mechanisms and scenarios.优先沿着 DNA 大沟漂移和 p53 核心结构域的协同锚定:机制和场景。
J Mol Recognit. 2010 Mar-Apr;23(2):232-40. doi: 10.1002/jmr.990.
8
A non-sequence-specific DNA binding mode of RAG1 is inhibited by RAG2.RAG2抑制RAG1的非序列特异性DNA结合模式。
J Mol Biol. 2009 Apr 3;387(3):744-58. doi: 10.1016/j.jmb.2009.02.020. Epub 2009 Feb 20.
9
Tumor suppressor p53 slides on DNA with low friction and high stability.肿瘤抑制因子p53在DNA上滑动时摩擦力低且稳定性高。
Biophys J. 2008 Jul;95(1):L01-3. doi: 10.1529/biophysj.108.134122. Epub 2008 Apr 18.
10
C-terminal diversity within the p53 family accounts for differences in DNA binding and transcriptional activity.p53家族内的C末端多样性导致DNA结合和转录活性的差异。
Nucleic Acids Res. 2008 Apr;36(6):1900-12. doi: 10.1093/nar/gkn044. Epub 2008 Feb 11.