Steinhoff G
Klinik und Poliklinik für Herzchirurgie, Medizinische Fakultät, Universität Rostock.
Internist (Berl). 2006 May;47(5):479-80, 482-4, 486-7. doi: 10.1007/s00108-006-1610-2.
The loss of contractile heart tissue - often a sequelae of cardiac infarction - is caused by the limited regeneration capacity of the heart and usually leads to irreversible organ damage. Modification of this regeneration capacity by cell-based cardiac therapies with precursor and stem cells opens a new therapeutic field. A number of different (stem)cell types and applications are currently being evaluated. The possibilities and risks of the therapy are not easily foreseeable, however, clinical applications are already visible. In the light of stem cell research, the vision of regrowth of the heart in analogy to the Prometheus saga is obtaining a scientific explanation and may lead to new cardiac therapies.
收缩性心脏组织的丧失——通常是心肌梗死的后遗症——是由心脏有限的再生能力引起的,并且通常会导致不可逆的器官损伤。通过使用前体细胞和干细胞进行基于细胞的心脏治疗来改变这种再生能力,开辟了一个新的治疗领域。目前正在评估多种不同的(干)细胞类型及其应用。然而,这种治疗的可能性和风险并非轻易就能预见,不过临床应用已经初见端倪。鉴于干细胞研究,类似于普罗米修斯传奇中让心脏再生的愿景正在得到科学解释,并且可能会带来新的心脏治疗方法。