大肠杆菌单污染无菌大鼠的肠绞窄。
Intestinal Strangulation in Escherichia coli-Monocontaminated Gnotobiotic Rats.
机构信息
Department of Surgery, University of Wisconsin Medical School, Madison, Wisconsin 53706.
出版信息
Infect Immun. 1970 Feb;1(2):195-9. doi: 10.1128/iai.1.2.195-199.1970.
The natural course of ischemic and hemorrhagic intestinal strangulation in previously germ-free rats individually monocontaminated with one of five separate strains of Escherichia coli was investigated. In addition, the effect of intraintestinal homologous heparinized blood upon the course of ischemic intestinal strangulation in E. coli-monocontaminated rats was studied. It was found that (i) E. coli could be an important lethal factor in ischemic and hemorrhagic intestinal strangulation, (ii) hemorrhagic was more deadly than ischemic strangulation, (iii) intra-intestinal blood did not augment the action of the E. coli in these experiments, and (iv) some strains of E. coli were more toxic than others in the presence of intestinal strangulation.
研究了先前无菌大鼠个体单独感染五种不同大肠杆菌菌株之一后，缺血性和出血性肠绞窄的自然病程。此外，还研究了肠内同源肝素化血液对大肠杆菌单一污染大鼠缺血性肠绞窄病程的影响。结果发现：（i）大肠杆菌可能是缺血性和出血性肠绞窄的重要致死因素；（ii）出血性绞窄比缺血性绞窄更致命；（iii）在这些实验中，肠内血液并没有增强大肠杆菌的作用；（iv）在存在肠绞窄的情况下，某些大肠杆菌菌株比其他菌株更具毒性。
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