National Institute of Allergy and Infectious Diseases, Rocky Mountain Laboratory, Hamilton, Montana 59840.
Infect Immun. 1970 Sep;2(3):256-9. doi: 10.1128/iai.2.3.256-259.1970.
In a study to determine susceptibility to Borrelia hermsii of various rodents commonly found in or near places where human cases of relapsing fever occurred, chipmunks (Eutamias amoenus), pine squirrels (Tamiasciurus hudsonicus richardsoni), flying squirrels (Glaucomys sabrinus), Columbian ground squirrels (Spermophilus columbianus columbianus), golden-mantled ground squirrels (S. lateralis tescorum), wood rats (Neotoma cinerea cinerea), white-footed deer mice (Peromyscus maniculatus), and meadow voles (Microtus pennsylvanicus) were exposed to spirochetes either by bites of infected Ornithodoros hermsi or by injection of infectious tick suspensions. Daily microscopic examination of blood samples revealed that pine squirrels, chipmunks, and meadow voles responded with spirochetemias of various degrees and length. Pine squirrels were most susceptible and experienced long-lasting and severe spirochetemias accompanied by typical signs of illness. Flying squirrels, Columbian ground squirrels, golden-mantled ground squirrels, wood rats, and white-footed deer mice did not develop demonstrable spirochetal infection.
在一项旨在确定各种常见于或接近回归热患者发生地的啮齿动物对伯氏疏螺旋体敏感性的研究中，研究人员通过感染了奥氏疏螺旋体的硬蜱叮咬或注射传染性蜱混悬液，使花栗鼠（Eutamias amoenus）、金花鼠（Tamiasciurus hudsonicus richardsoni）、鼯鼠（Glaucomys sabrinus）、哥伦比亚地松鼠（Spermophilus columbianus columbianus）、金冠松鼠（S. lateralis tescorum）、林姬鼠（Neotoma cinerea cinerea）、白足鼠（Peromyscus maniculatus）和草原田鼠（Microtus pennsylvanicus）接触到螺旋体。每天对血液样本进行显微镜检查显示，金花鼠、花栗鼠和草原田鼠对不同程度和持续时间的螺旋体血症有反应。金花鼠最易感，经历了持久和严重的螺旋体血症，并伴有典型的疾病迹象。鼯鼠、哥伦比亚地松鼠、金冠松鼠、林姬鼠和白足鼠没有出现可检测到的螺旋体感染。
