5-氟尿嘧啶和5-氟脱氧尿苷对根癌土壤杆菌生长及致瘤能力的影响
Effects of 5-Fluorouracil and 5-Fluorodeoxyuridine on Growth and Tumor-Inducing Ability of Agrobacterium tumefaciens.
作者信息
Beardsley R E, Lipetz J
机构信息
Laboratory of Plant Morphogenesis, Manhattan College, Bronx, New York.
出版信息
J Bacteriol. 1966 Aug;92(2):346-8. doi: 10.1128/jb.92.2.346-348.1966.
Beardsley, Robert E. (Manhattan College, Bronx, N.Y.), and Jacques Lipetz Effects of 5-fluorouracil and 5-fluorodeoxyuridine on growth and tumor-inducing ability of Agrobacterium tumefaciens. J. Bacteriol. 92:346-348. 1966.-Agrobacterium tumefaciens B6, grown in the presence of 5-fluorouracil or 5-fluodeoxyuridine, exhibited a prolonged lag phase. The tumor-inducing ability of bacteria grown in the presence of these compounds was decreased even after exposures as short as 40 min. A positive correlation was found between the growth-inhibitory effects of these compounds and their effects on the tumor-inducing ability of the bacteria.
比尔兹利，罗伯特·E.（纽约州布朗克斯曼哈顿学院），以及雅克·利佩茨。5-氟尿嘧啶和5-氟脱氧尿苷对根癌土壤杆菌生长和致瘤能力的影响。《细菌学杂志》92:346 - 348。1966年。——在5-氟尿嘧啶或5-氟脱氧尿苷存在下生长的根癌土壤杆菌B6，表现出延长的延迟期。即使在短至40分钟的暴露后，在这些化合物存在下生长的细菌的致瘤能力也会降低。发现这些化合物的生长抑制作用与其对细菌致瘤能力的影响之间存在正相关。
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