Stonier T, Beardsley R E, Parsons L, McSharry J
J Bacteriol. 1966 Jan;91(1):266-9. doi: 10.1128/jb.91.1.266-269.1966.
Stonier, Tom (Manhattan College, Bronx, N.Y.), Robert E. Beardsley, Lowell Parsons, and James McSharry. Agrobacterium tumefaciens Conn. III. Effect of thermal shock on bacteria in relation to tumor-inducing ability. J. Bacteriol. 91:266-269. 1966.-Bacteria heated to 42 C for 30 min exhibit a decrease in tumor-initiating ability without a detectable loss in viability. The thermal shock inhibits subsequent bacterial growth for up to 1.5 hr. As bacterial growth recovers, so does tumor-initiating ability. Respiration of the culture is somewhat increased by the heat treatment. The data suggest that living, actively respiring bacteria do not induce tumors unless they are also growing. The results also point to the necessity for excluding bacterial growth inhibition when interpreting data on the effect of various agents on tumor initiation.
斯托尼尔，汤姆（纽约州布朗克斯曼哈顿学院），罗伯特·E·比尔兹利，洛厄尔·帕森斯，以及詹姆斯·麦克沙里。根癌土壤杆菌康恩。III。热休克对细菌的影响与肿瘤诱导能力的关系。《细菌学杂志》91:266 - 269。1966年。-加热至42摄氏度30分钟的细菌，其肿瘤引发能力下降，但活力无明显损失。热休克会抑制细菌后续生长长达1.5小时。随着细菌生长恢复，肿瘤引发能力也会恢复。热处理会使培养物的呼吸作用有所增强。数据表明，存活且积极呼吸的细菌除非正在生长，否则不会诱导肿瘤。结果还指出，在解释各种因素对肿瘤引发的影响的数据时，排除细菌生长抑制的必要性。
