Meffan P J, Delahunt B, Nacey J N
Wellington Hospital.
N Z Med J. 1991 Sep 25;104(920):393-4.
A study of 79 patients treated at Wellington Hospital for testicular cancer showed that those presenting with a short history (time from tumour recognition to surgery) had no better prognosis than those with a longer history (chi 2 = 1.857, p = 0.173). Tumour size was significantly related to this time interval such that those patients with a short history were more likely to have smaller tumours (rp = 0.651, p = 0.001). The data suggests that testicular tumours are currently being recognised too late in their development to allow any improvement in survival to be gained from reducing the interval from recognition to treatment. However, earlier recognition of the tumour by the patient may allow diagnosis and treatment in an earlier stage. The advantages of diagnosis in early stage disease are substantial and the need for a public education programme involving testicular self examination to allow early diagnosis is discussed.
一项针对在惠灵顿医院接受睾丸癌治疗的79名患者的研究表明,那些病程较短(从肿瘤确诊到手术的时间)的患者,其预后并不比病程较长的患者更好(卡方检验值=1.857,p=0.173)。肿瘤大小与这一时间间隔显著相关,即病程较短的患者更有可能患有较小的肿瘤(相关系数rp=0.651,p=0.001)。数据表明,目前睾丸肿瘤在其发展过程中被识别得太晚,以至于无法通过缩短从确诊到治疗的间隔时间来提高生存率。然而,患者更早地识别肿瘤可能有助于在更早阶段进行诊断和治疗。早期疾病诊断的益处显著,文中还讨论了开展一项涉及睾丸自我检查的公众教育项目以实现早期诊断的必要性。