Vercellini Paolo, Viganò Paola, Somigliana Edgar, Daguati Raffaella, Abbiati Annalisa, Fedele Luigi
Department of Obstetrics and Gynaecology, University of Milan, and the Centre for Research in Obstetrics and Gynaecology, Milan, Italy.
Best Pract Res Clin Obstet Gynaecol. 2006 Aug;20(4):465-77. doi: 10.1016/j.bpobgyn.2006.01.017. Epub 2006 Mar 24.
Epidemiological studies of adenomyosis are difficult to interpret because the diagnostic criteria vary so widely that the disease may be easily over-diagnosed. This would severely hamper any attempt to define incidence and prevalence of the condition and the related risk factors, and would limit the possibility of clarifying to what extent adenomyosis contributes to clinical symptoms. There is a need for stringent and widely accepted diagnostic criteria in order to define not only the presence of adenomyosis but also depth of penetration and degree of spread of foci. Moreover, the evidence available on epidemiological characteristics of women with adenomyosis is greatly biased by the type of population studied, i.e. women undergoing hysterectomy. Therefore, a consensus on non-surgical diagnostic criteria at transvaginal ultrasonography and MRI is indispensable and urgently needed in order to be able to conduct epidemiological studies in women younger than those evaluated until now.
子宫腺肌病的流行病学研究难以解读,因为诊断标准差异极大,以至于该病可能很容易被过度诊断。这将严重阻碍任何界定该疾病发病率、患病率及相关危险因素的尝试,并会限制阐明子宫腺肌病在何种程度上导致临床症状的可能性。需要有严格且被广泛接受的诊断标准,以便不仅能界定子宫腺肌病的存在,还能界定病灶的浸润深度和扩散程度。此外,现有关于子宫腺肌病女性流行病学特征的证据因所研究人群的类型(即接受子宫切除术的女性)而存在极大偏差。因此,对于经阴道超声检查和磁共振成像的非手术诊断标准达成共识是不可或缺且迫切需要的,以便能够在比目前所评估的女性更年轻的人群中开展流行病学研究。