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先天性矫正型大动脉转位的生理性与解剖性修复:个体患者数据的荟萃分析

Physiologic versus anatomic repair of congenitally corrected transposition of the great arteries: meta-analysis of individual patient data.

作者信息

Alghamdi Abdullah A, McCrindle Brian W, Van Arsdell Glen S

机构信息

Division of Cardiac Surgery, Congenital Cardiac Surgery Program, Department of Surgery, University of Toronto, Toronto, Ontario, Canada.

出版信息

Ann Thorac Surg. 2006 Apr;81(4):1529-35. doi: 10.1016/j.athoracsur.2005.09.035.

Abstract

The objective of this meta-analysis of individual patients' data was to compare the immediate outcomes of anatomic and physiologic repair of congenitally corrected transposition of the great arteries. Eleven nonrandomized studies, involving 124 patients, met the inclusion criteria for this review. The Rastelli type anatomic repair and the era of surgery were significantly related to the outcome in different tested models. Entering all variables into the logistic regression model showed a significant protective effect of the Rastelli type anatomic repair (odds ratio = 0.05, 95% confidence interval: 0.01, 0.50, p = 0.02).

摘要

这项个体患者数据的荟萃分析旨在比较先天性矫正型大动脉转位的解剖修复和生理修复的近期疗效。11项非随机研究,涉及124例患者,符合本综述的纳入标准。在不同的测试模型中,Rastelli型解剖修复和手术时代与疗效显著相关。将所有变量纳入逻辑回归模型显示,Rastelli型解剖修复具有显著的保护作用(比值比=0.05,95%置信区间:0.01,0.50,p=0.02)。

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