小动物遗传学的最新进展。

Recent advances in small animal genetics.

作者信息

Bannasch Danika L, Hughes Angela M

机构信息

Veterinary Medical Teaching Hospital, School of Veterinary Medicine, One Shields Avenue, University of California at Davis, Davis, CA 95616, USA.

出版信息

Vet Clin North Am Small Anim Pract. 2006 May;36(3):461-74, v. doi: 10.1016/j.cvsm.2005.12.004.

DOI:10.1016/j.cvsm.2005.12.004

PMID:16564409

Abstract

The whole genome sequence of the dog is complete, and partial sequencing of the cat genome is underway. Sequences allow the molecular basis for inherited diseases to be more easily determined, leading to development of DNA tests to verify carrier and affected states as well as potential gene therapy for the treatment of those diseases. To help veterinarians provide genetic services to their clients, the molecular genetic tests currently available are listed in this article. In addition, cloning of small animals is now available to clients on a commercial basis. Information about the cloning process and possible health issues in clones are discussed.

摘要

狗的全基因组序列已完成，猫基因组的部分测序正在进行中。序列使遗传性疾病的分子基础更容易确定，从而推动了DNA检测的发展，以验证携带者和患病状态，以及针对这些疾病的潜在基因治疗。为帮助兽医为客户提供遗传服务，本文列出了目前可用的分子遗传检测。此外，现在客户可以在商业基础上获得小动物克隆服务。文中讨论了克隆过程及克隆体可能存在的健康问题。