Seto H, Kageyama M, Nomura K, Kakishita M, Tonami S
Department of Radiological Sciences, Toyama Medical and Pharmaceutical University, Japan.
Radiat Med. 1991 May-Jun;9(3):110-3.
The precision of total-body and regional bone mineral measurements from whole body scans obtained by dual-energy X-ray absorptiometry (DEXA) was determined in a phantom and two normal subjects. Whole body scans were performed once a week for three months at the speed of 80 mm/sec. Coefficients of variation for measurements of total-body bone mineral content (BMC) in the phantom and the subjects were 1.7% and 1.5% (average), respectively. Moreover, plots of total-body BMC values with time showed no significant slope, indicating the stability of the instrument. Regional BMC measurement from whole body scans, however, resulted in larger precision errors than total-body BMC measurement. This is attributed to the more rapid scan speed and coarser scan width used in whole body scanning as compared with regional scanning. Good precision of total-body BMC measurement by DEXA is of great clinical value in the assessment of metabolic bone disease.
通过双能X线吸收法（DEXA）对全身扫描所得的全身及局部骨矿物质测量的精密度，在一个模型和两名正常受试者中进行了测定。以80毫米/秒的速度，每周进行一次全身扫描，共持续三个月。模型和受试者中全身骨矿物质含量（BMC）测量的变异系数分别为1.7%和1.5%（平均）。此外，全身BMC值随时间的变化曲线未显示出显著斜率，表明仪器的稳定性。然而，全身扫描的局部BMC测量产生的精密度误差比全身BMC测量更大。这归因于与局部扫描相比，全身扫描使用的扫描速度更快且扫描宽度更粗。DEXA进行的全身BMC测量的良好精密度在代谢性骨病的评估中具有重要的临床价值。
