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Endothelins and sarafotoxins: physiological regulation, receptor subtypes and transmembrane signaling.

作者信息

Sokolovsky M

机构信息

Department of Biochemistry, George S. Wise Faculty of Life Sciences, Tel Aviv University, Israel.

出版信息

Trends Biochem Sci. 1991 Jul;16(7):261-4. doi: 10.1016/0968-0004(91)90100-a.

DOI:10.1016/0968-0004(91)90100-a
PMID:1656557
Abstract

The endothelins and sarafotoxins are two structurally related families of potent vasoactive peptides. Although the exact physiological function of these peptides is not known, the endothelins are probably involved in pathophysiological conditions such as hypertension and heart failure. This article will review the biochemistry of these peptides and their receptors, with special reference to proteolytic regulation, receptor subtypes and the G protein-linked phosphoinositide signal transduction pathway.

摘要

相似文献

1
Endothelins and sarafotoxins: physiological regulation, receptor subtypes and transmembrane signaling.
Trends Biochem Sci. 1991 Jul;16(7):261-4. doi: 10.1016/0968-0004(91)90100-a.
2
Endothelins and sarafotoxins: physiological regulation, receptor subtypes and transmembrane signaling.
Pharmacol Ther. 1992;54(2):129-49. doi: 10.1016/0163-7258(92)90030-4.
3
Structure-function relationships of endothelins, sarafotoxins, and their receptor subtypes.内皮素、萨拉托毒素及其受体亚型的结构-功能关系。
J Neurochem. 1992 Sep;59(3):809-21. doi: 10.1111/j.1471-4159.1992.tb08318.x.
4
Similarities in mode and sites of action of sarafotoxins and endothelins.
Trends Pharmacol Sci. 1989 Jun;10(6):212-4. doi: 10.1016/0165-6147(89)90261-7.
5
Endothelin receptor heterogeneity, G-proteins, and signaling via cAMP and cGMP cascades.内皮素受体异质性、G蛋白以及通过环磷酸腺苷（cAMP）和环磷酸鸟苷（cGMP）级联反应的信号传导。
Cell Mol Neurobiol. 1995 Oct;15(5):561-71. doi: 10.1007/BF02071317.
6
Competitive interaction between endothelin and sarafotoxin: Binding and phosphoinositides hydrolysis in rat atria and brain.内皮素与芋螺毒素之间的竞争性相互作用：大鼠心房和大脑中的结合及磷酸肌醇水解
Biochem Biophys Res Commun. 1989 Jan 16;158(1):195-201. doi: 10.1016/s0006-291x(89)80197-4.
7
Truncated analogues of endothelin and sarafotoxin are selective for the ETB receptor subtype.内皮素和尾加压素的截短类似物对ETB受体亚型具有选择性。
Pept Res. 1993 Sep-Oct;6(5):238-41.
8
Endothelins and sarafotoxins: peptides of similar structure and different function.内皮素和沙巴毒素：结构相似但功能不同的肽类。
Acta Medica (Hradec Kralove). 2004;47(3):157-62.
9
The development of potent peptide agonists and antagonists for the endothelin receptors.用于内皮素受体的强效肽激动剂和拮抗剂的研发。
Biopolymers. 1995;37(2):89-104. doi: 10.1002/bip.360370205.
10
Structure-receptor binding relationships of sarafotoxin and endothelin in porcine cardiovascular tissues.猪心血管组织中萨拉毒素与内皮素的结构-受体结合关系
Biochem Int. 1990 Sep;21(6):1059-64.

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Endothelin Inhibitors in Chronic Kidney Disease: New Treatment Prospects.慢性肾脏病中的内皮素抑制剂：新的治疗前景
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Respiratory Effects of Sarafotoxins from the Venom of Different Atractaspis Genus Snake Species.不同种类穴蝰属蛇毒中萨拉毒素的呼吸效应
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PLoS One. 2015 Jul 15;10(7):e0132864. doi: 10.1371/journal.pone.0132864. eCollection 2015.
4
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Cell Mol Life Sci. 2015 May;72(10):1939-58. doi: 10.1007/s00018-015-1844-z. Epub 2015 Feb 19.
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Endothelin receptor subtype distribution predisposes coronary arteries to damage.内皮素受体亚型分布使冠状动脉易受损伤。
Am J Pathol. 2000 Jul;157(1):123-34. doi: 10.1016/S0002-9440(10)64524-5.
6
Differential localization of endothelin ETA and ETB binding sites in human placenta.内皮素ETA和ETB结合位点在人胎盘中的差异定位。
Br J Pharmacol. 1993 Jun;109(2):544-52. doi: 10.1111/j.1476-5381.1993.tb13605.x.
7
Interaction of atrial natriuretic factor and endothelin-1 signals through receptor guanylate cyclase in pulmonary artery endothelial cells.心房利钠因子与内皮素-1信号在肺动脉内皮细胞中通过受体鸟苷酸环化酶相互作用。
Mol Cell Biochem. 1993 Mar 10;120(1):69-80. doi: 10.1007/BF00925986.
8
HomologyPlot: searching for homology to a family of proteins using a database of unique conserved patterns.同源性绘图：利用独特保守模式数据库搜索与蛋白质家族的同源性。
J Comput Aided Mol Des. 1994 Apr;8(2):193-210. doi: 10.1007/BF00119867.