Mitnick J S, Vazquez M F, Roses D F, Harris M N, Gianutsos R, Waisman J
Department of Radiology, Kaplan Cancer Center, Tisch Hospital, New York, NY.
Arch Surg. 1991 Sep;126(9):1137-40. doi: 10.1001/archsurg.1991.01410330099014.
The efficacy of stereotaxic aspiration biopsy was evaluated in 300 consecutive patients with nonpalpable mammographic lesions. Sixty-eight patients (23%) had suspicious or malignant aspirates; all cases were proved malignant by subsequent examination of operative specimens. Two hundred sixteen patients (72%) had benign aspirates. Of these, 65 were confirmed by operation and 151 had subsequent mammography at 6- and 12-month intervals with no demonstrable mammographic change. In 10 instances (3%), the aspirates were atypical, and in six (2%), nondiagnostic. Biopsy specimens were obtained in all 16 instances, and eight were malignant. The sensitivity of stereotaxic breast aspiration for the diagnosis of cancer was 96%, and the specificity was 100%. Our experience confirms the efficacy of stereotaxic aspiration for the initial evaluation of mammographically detected, nonpalpable lesions.
对300例乳腺钼靶检查发现的不可触及性病变患者进行了立体定向针吸活检的疗效评估。68例患者（23%）针吸物可疑或为恶性；所有病例经手术标本后续检查均证实为恶性。216例患者（72%）针吸物为良性。其中，65例经手术证实，151例在术后6个月和12个月进行了乳腺钼靶复查，未发现乳腺钼靶有明显变化。10例（3%）针吸物不典型，6例（2%）为无法诊断。对这16例均进行了活检，其中8例为恶性。立体定向乳腺针吸诊断癌症的敏感性为96%，特异性为100%。我们的经验证实了立体定向针吸在乳腺钼靶检查发现的不可触及性病变初始评估中的有效性。
