D'Antono Bianca, Dupuis Gilles, Fortin Christophe, Arsenault André, Burelle Denis
Montreal Heart Institute, Montreal, Quebec, Canada. bianca.d'
Am Heart J. 2006 Apr;151(4):813-9. doi: 10.1016/j.ahj.2005.06.028.
To examine sex differences in pain and associated symptoms in patients with exercise-related ischemia, as well as the independence of these findings from other clinical factors.
Prospective study of 482 women and 425 men (mean age 58 years) undergoing exercise stress testing with myocardial perfusion imaging (MPI). Analyses were performed on 38 women and 94 men with both angina and MPI evidence of ischemia during exercise.
Chest pain localization, extension, intensity, quality, and presence of various non-pain-related symptoms.
Women rated their pain as more intense, used different words to describe it, and reported more non-pain-related symptoms than men (P < .05). They experienced pain and other sensations in the neck area more frequently (P < .05). Most of these differences remained after controlling for clinical or psychological variables, with the exception of pain intensity measures.
Sex differences in the experience of symptoms associated with MPI evidence of myocardial ischemia may complicate timely and accurate diagnosis of ischemia in women.
研究运动相关缺血患者疼痛及相关症状的性别差异，以及这些发现与其他临床因素的独立性。
对482名女性和425名男性（平均年龄58岁）进行运动应激试验及心肌灌注成像（MPI）的前瞻性研究。对38名女性和94名男性进行分析，这些患者在运动期间既有心绞痛又有MPI缺血证据。
胸痛的定位、范围、强度、性质以及各种与疼痛无关的症状的存在情况。
女性对疼痛的评分更高，用不同的词语描述疼痛，并且比男性报告更多与疼痛无关的症状（P <.05）。她们在颈部区域更频繁地经历疼痛和其他感觉（P <.05）。除疼痛强度测量外，在控制临床或心理变量后，这些差异大多仍然存在。
与MPI心肌缺血证据相关的症状体验中的性别差异可能会使女性缺血的及时准确诊断复杂化。
