Winzer K J, Guski H, Frohberg H D
Klinik für Chirurgie, Medizinischen Fakultät, Charité, Humboldt-Universität zu Berlin.
Zentralbl Pathol. 1991;137(3):260-3.
Non-invasive mammary carcinoma can be surgically treated with preservation of the breast even without adjuvant radiotherapy, if all necessary conditions are provided, such as accurate indication, absence of multicentricity, no involvement of mamillae except of Paget's disease, tumour diameter not more than 20 mm as well as efficient and systematic performance of intraoperative diagnostic histology. An analysis of the author's own surgical findings revealed multicentricity in 16% of all cases of intraductal carcinoma. Breast-preserving operations could be performed on 63% of the patients. Local recurrences were recorded from 13% of all cases reviewed. The rate of breast-preserving operations with lowest possible rate of recurrence, by all accounts of experience, can be enhanced only by close interdisciplinary cooperation among radiologists, surgeons, and pathologists.
如果具备所有必要条件，如准确的指征、无多中心性、除派杰氏病外乳头未受累、肿瘤直径不超过20毫米以及术中诊断性组织学的高效系统操作，非侵袭性乳腺癌即使不进行辅助放疗也可通过保乳手术进行治疗。作者自身手术结果分析显示，在所有导管内癌病例中，16%存在多中心性。63%的患者可行保乳手术。在所有回顾的病例中，13%记录有局部复发。根据所有经验，只有放射科医生、外科医生和病理学家之间密切的多学科合作，才能提高保乳手术的复发率尽可能低。
