Winzer K J, Guski H, Frohberg H D
Klinik für Chirurgie, Medizinischen Fakultät, Charité, Humboldt-Universität zu Berlin.
Zentralbl Pathol. 1991;137(3):260-3.
Non-invasive mammary carcinoma can be surgically treated with preservation of the breast even without adjuvant radiotherapy, if all necessary conditions are provided, such as accurate indication, absence of multicentricity, no involvement of mamillae except of Paget's disease, tumour diameter not more than 20 mm as well as efficient and systematic performance of intraoperative diagnostic histology. An analysis of the author's own surgical findings revealed multicentricity in 16% of all cases of intraductal carcinoma. Breast-preserving operations could be performed on 63% of the patients. Local recurrences were recorded from 13% of all cases reviewed. The rate of breast-preserving operations with lowest possible rate of recurrence, by all accounts of experience, can be enhanced only by close interdisciplinary cooperation among radiologists, surgeons, and pathologists.