西地那非对接受RigiScan Plus视听性刺激（AVSS）测试的日本患者的疗效。

Efficacy of sildenafil for Japanese patients with audio-visual sexual stimulation (AVSS) test by the RigiScan Plus.

作者信息

Soh J, Naya Y, Ushijima S, Naitoh Y, Ochiai A, Mizutani Y, Kawauchi A, Miki T, Fujiwara T

机构信息

Department of Urology, Graduate School Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.

出版信息

Arch Androl. 2006 May-Jun;52(3):163-8. doi: 10.1080/01485010500379889.

DOI:10.1080/01485010500379889

PMID:16574596

Abstract

Sildenafil is most effective in men with mild-to-moderate ED, but not severe ED in Japan. In order to evaluate the efficacy of sildenafil, we conducted the present study using the AVSS test by the RigiScan Plus. The subjects were 56 patients (age: 34-82 years, mean: 60.5 years) with ED. The IIEF5 questionnaire and the AVSS test were conducted before and after administration of sildenafil. The penile rigidity could not be measured in 19 patients. Of these 19, sildenafil was effective in 7 and not effective in 12. The 7 cases in whom sildenafil was effective were all false-negatives. The sensitivity of sildenafil was 84%, and its specificity was 100%. This study suggests that the AVSS test by RigiScan Plus can objectively evaluate the efficacy of sildenafil, and shows potential for predicting that efficacy.

摘要

在日本，西地那非对轻度至中度勃起功能障碍（ED）男性最为有效，但对重度ED无效。为了评估西地那非的疗效，我们使用RigiScan Plus的视听性刺激敏感度测试（AVSS测试）进行了本研究。研究对象为56例ED患者（年龄：34 - 82岁，平均60.5岁）。在服用西地那非前后进行了国际勃起功能指数-5（IIEF5）问卷和AVSS测试。19例患者无法测量阴茎硬度。在这19例患者中，西地那非对7例有效，对12例无效。西地那非有效的7例均为假阴性。西地那非的敏感度为84%，特异度为100%。本研究表明，RigiScan Plus的AVSS测试能够客观评估西地那非的疗效，并显示出预测该疗效的潜力。