David R, Rawlinson J, Ferguson K M
Arch Dis Child. 1975 Feb;50(2):157-60. doi: 10.1136/adc.50.2.157.
A case of sexual precocity of unusually early onset and associated with a hypothalamic tumour is described. The effects of ethinyl oestradiol and medroxyprogesterone acetate treatment have been monitored by plasma testosterone, FSH, and LH estimations. The results suggested a partial suppression of the tumour's influence, the mechanism of which is discussed.
本文描述了一例起病异常早且与下丘脑肿瘤相关的性早熟病例。通过检测血浆睾酮、促卵泡激素(FSH)和促黄体生成素(LH),监测了炔雌醇和醋酸甲羟孕酮治疗的效果。结果提示肿瘤的影响得到了部分抑制,并对其机制进行了讨论。