Dixon Simon, Morgan Kevin, Mathers Nigel, Thompson Joanne, Tomeny Maureen
School of Health and Related Research, University of Sheffield, and Department of Clinical Psychology, Nottinghamshire Healthcare Trust, England.
Behav Sleep Med. 2006;4(2):71-84. doi: 10.1207/s15402010bsm0402_1.
Results were combined from representative surveys of health related quality of life (HRQoL; n=11,877; age range=16-104) with data from a randomized controlled trial of cognitive behavior therapy for chronic insomnia (n=209; age range=31-92). Secondary analyses of scores from the SF-36 measure of HRQoL were conducted in order: (a) to compare the health related quality of life profiles of adult hypnotic users with chronic insomnia with those of population norms, and (b) to assess the impact of cognitive behavior therapy (CBT) for insomnia on HRQoL outcomes over 6 months. Compared with the primary care reference values, HRQoL among the trial participants at baseline was generally poorer. The magnitude of these decrements reduced markedly with advancing age. In the evaluation of the CBT intervention, statistically significant differences in SF-36 scores in favor of the intervention were present for physical functioning, emotional role limitation, and mental health over 6 months. Overall, this study shows that the SF-36 can play an important role in describing HRQoL in this patient group, and in the evaluation of interventions within this group.
研究结果综合了健康相关生活质量(HRQoL;n = 11,877;年龄范围 = 16 - 104岁)的代表性调查数据以及一项针对慢性失眠的认知行为疗法随机对照试验(n = 209;年龄范围 = 31 - 92岁)的数据。对HRQoL的SF - 36测量得分进行了二次分析,目的如下:(a) 将成年慢性失眠催眠药物使用者的健康相关生活质量概况与总体标准进行比较;(b) 评估失眠认知行为疗法(CBT)对6个月内HRQoL结果的影响。与初级保健参考值相比,试验参与者基线时的HRQoL总体较差。随着年龄增长,这些下降幅度明显减小。在CBT干预评估中,6个月内SF - 36得分在身体功能、情感角色限制和心理健康方面存在有利于干预的统计学显著差异。总体而言,本研究表明SF - 36在描述该患者群体的HRQoL以及评估该群体内的干预措施方面可发挥重要作用。