Wu Jennifer M, Williams Kathryn S, Hundley Andrew F, Jannelli Mary L, Visco Anthony G
Department of Obstetrics and Gynecology, University of North Carolina, Chapel Hill, NC, USA.
Am J Obstet Gynecol. 2006 May;194(5):1423-6. doi: 10.1016/j.ajog.2006.01.053. Epub 2006 Mar 30.
The purpose of this study was to assess microscopic hematuria as a predictive factor for detecting bladder cancer at cystoscopy in women with irritative voiding symptoms.
We conducted a retrospective cohort analysis of women with irritative voiding symptoms who presented for urodynamic testing and cystoscopy. Irritative voiding symptoms were defined as urgency, urge incontinence, frequency, dysuria, and/or nocturia. Patient demographics, risk factors for bladder cancer, presence of microscopic hematuria, urodynamic findings, and cystoscopy and biopsy results were recorded.
Of 735 patients with irritative voiding symptoms, 264 (35.9%) had microscopic hematuria and 471 (64.1%) had no hematuria. Bladder cancer was detected in 3 women, for an overall detection rate of 0.4%. Microscopic hematuria, urgency, frequency, dysuria, nocturia, age, and tobacco use were not significantly associated with bladder cancer.
In this cohort of women with irritative voiding symptoms, microscopic hematuria was not predictive for bladder cancer.
本研究旨在评估镜下血尿作为有刺激性排尿症状女性膀胱镜检查时膀胱癌检测预测因素的价值。
我们对因进行尿动力学检查和膀胱镜检查而出现刺激性排尿症状的女性进行了一项回顾性队列分析。刺激性排尿症状定义为尿急、急迫性尿失禁、尿频、尿痛和/或夜尿症。记录患者的人口统计学数据、膀胱癌风险因素、镜下血尿的存在情况、尿动力学检查结果以及膀胱镜检查和活检结果。
在735例有刺激性排尿症状的患者中，264例（35.9%）有镜下血尿，471例（64.1%）无血尿。3名女性被检测出患有膀胱癌，总体检出率为0.4%。镜下血尿、尿急、尿频、尿痛、夜尿症、年龄和吸烟与膀胱癌无显著相关性。
在这组有刺激性排尿症状的女性中，镜下血尿不能预测膀胱癌。
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