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择期剖宫产术后新生儿呼吸系统发病率

Neonatal respiratory morbidity after elective cesarean section.

作者信息

Many Ariel, Helpman Limor, Vilnai Yael, Kupferminc Michael J, Lessing Joseph B, Dollberg Shaul

机构信息

Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

J Matern Fetal Neonatal Med. 2006 Feb;19(2):75-8. doi: 10.1080/14767050500333868.

Abstract

OBJECTIVE

The objective of this study was to examine the rate of respiratory morbidity in neonates delivered by elective cesarean delivery (ECD) at term, with a definite confirmation of gestational age (GA) by 1st-trimester ultrasound.

METHODS

Consecutive women carrying a singleton pregnancy and undergoing ECD at term (>38 1/7 weeks), confirmed by 1st-trimester ultrasound, were included in the study group. Multiple gestations, cesarean section (CS) in labor, CS performed after rupture of membranes and induced deliveries were excluded. The control group included women with a singleton pregnancy at term (>38 1/7 weeks) who delivered spontaneously. This group of women was randomly selected during the study period.

RESULTS

The study group included 277 women delivered by ECD. The control group consisted of 311 women. Five newborns in the study group and none in the control group were admitted to the neonatal intensive care unit (NICU) due to respiratory disorders (p < 0.02). Excluding diabetic women did not change the results. On multivariate analysis, no other factors were found to independently influence the risk of respiratory complications.

CONCLUSION

In our study, the rate of respiratory morbidity was found to be significantly higher in neonates delivered by ECD compared to those delivered vaginally. The fact that GA was confirmed by 1st-trimester ultrasound makes iatrogenic prematurity an unlikely sole cause for this excess morbidity.

摘要

目的

本研究的目的是调查足月择期剖宫产(ECD)分娩的新生儿的呼吸道疾病发生率,这些新生儿的孕周(GA)已通过孕早期超声明确确认。

方法

纳入研究组的是连续的单胎妊娠妇女,她们在足月(>38 1/7周)接受ECD,孕周经孕早期超声确认。排除多胎妊娠、分娩时剖宫产(CS)、胎膜破裂后进行的CS和引产。对照组包括足月(>38 1/7周)单胎妊娠且自然分娩的妇女。这组妇女是在研究期间随机选择的。

结果

研究组包括277例经ECD分娩的妇女。对照组由311例妇女组成。研究组中有5例新生儿因呼吸障碍入住新生儿重症监护病房(NICU),而对照组无新生儿因呼吸障碍入住(p<0.02)。排除糖尿病妇女后结果未改变。多因素分析未发现其他因素独立影响呼吸并发症的风险。

结论

在我们的研究中,发现ECD分娩的新生儿呼吸道疾病发生率显著高于阴道分娩的新生儿。孕早期超声确认孕周这一事实使得医源性早产不太可能是这种额外发病率的唯一原因。

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