Graziosi G C, Bakker C M, Brouwers H A, Bruinse H W
Academisch Ziekenhuis, afd. Obstetrie en Gynaecologie, Utrecht.
Ned Tijdschr Geneeskd. 1998 Oct 17;142(42):2300-3.
To determine the frequency of neonatal respiratory morbidity following elective caesarean delivery at term and to identify prognostic factors for this morbidity.
Retrospective.
Academic Hospital Utrecht/Wilhelmina Children's Hospital Neonatal Intensive Care Unit, Utrecht, the Netherlands.
All elective caesarean deliveries in the Academic Hospital Utrecht from the period 1990-1995 were studied. Also, neonates were included who were admitted for intensive neonatal care because of respiratory insufficiency following elective caesarean delivery in the region surrounding Utrecht. An elective caesarean delivery was defined as a delivery performed after 37 weeks of gestation without any complicating factor that might influence the timing of delivery. Prognostic factors for neonatal morbidity after caesarean delivery were identified by multivariate logistic regression analysis.
During 1990-1995, 272 elective caesarean deliveries after 37 weeks of gestation were performed that fulfilled the inclusion criteria; 5.1% of the neonates were admitted to the medium care unit because of respiratory problems. The relative risk of respiratory morbidity after delivery by caesarean section with a gestational age of 39-42 weeks compared with a gestational age of 37-38 weeks, was 0.14 (95% confidence interval: 0.03-0.64; p < 0.001). Male sex was a cofactor. Nine neonates of whom 8 (90%) had a gestational age of less than 39 weeks were admitted to the intensive care unit.
Most of neonatal respiratory morbidity could have been avoided by postponement of the at-term elective caesarean section until a certain gestational age of at least 38 complete weeks. An elective caesarean section should not be performed before that period.
确定足月择期剖宫产术后新生儿呼吸疾病的发生率,并找出该疾病的预后因素。
回顾性研究。
荷兰乌得勒支学术医院/威廉明娜儿童医院新生儿重症监护病房。
对1990年至1995年期间在乌得勒支学术医院进行的所有择期剖宫产进行研究。此外,纳入因乌得勒支周边地区择期剖宫产术后呼吸功能不全而入住新生儿重症监护病房的新生儿。择期剖宫产定义为妊娠37周后进行的分娩,且无任何可能影响分娩时间的复杂因素。通过多因素逻辑回归分析确定剖宫产术后新生儿发病的预后因素。
1990年至1995年期间,共进行了272例符合纳入标准的妊娠37周后的择期剖宫产;5.1%的新生儿因呼吸问题入住中级护理病房。与孕37 - 38周相比,孕39 - 42周剖宫产术后呼吸疾病的相对风险为0.14(95%置信区间:0.03 - 0.64;p < 0.001)。男性是一个辅助因素。9名新生儿入住重症监护病房,其中8名(90%)孕周小于39周。
通过将足月择期剖宫产推迟到至少38足周的特定孕周,大多数新生儿呼吸疾病本可避免。在此之前不应进行择期剖宫产。