Bosanquet A G, Ishimaru J, Goss A N
Department of Dentistry, University of Adelaide, South Australia.
J Oral Maxillofac Surg. 1991 Nov;49(11):1204-9. doi: 10.1016/0278-2391(91)90417-k.
The effect of Silastic (Dow Corning, Midland, MI) replacement following discectomy was examined in sheep temporomandibular joints (TMJs). Four sheep had disc perforations created bilaterally, and 20 weeks later the right disc was removed and replaced with a Silastic sheet. At 40 weeks following commencement of the study, the sheep were killed and the TMJs examined radiologically and histologically. The TMJs of two unoperated sheep were similarly evaluated to determine normal findings. Radiologic examination showed destructive bony change in all four operated joints. Histologic examination confirmed these bony changes in both the temporal bone and condyle. There were foreign particles with an accompanying foreign-body reaction throughout the fibrous tissue capsule that had formed around the implant.
在绵羊颞下颌关节（TMJ）中研究了椎间盘切除术后硅橡胶（道康宁公司，密歇根州米德兰）置换的效果。对四只绵羊双侧制造椎间盘穿孔，20周后切除右侧椎间盘并用硅橡胶片进行置换。在研究开始后的40周，处死绵羊并对TMJ进行放射学和组织学检查。对两只未手术绵羊的TMJ进行类似评估以确定正常表现。放射学检查显示所有四个手术关节均有骨质破坏改变。组织学检查证实颞骨和髁突均有这些骨质改变。在植入物周围形成的纤维组织囊内存在伴有异物反应的异物颗粒。
