Okazaki A, Okazaki M, Asaishi K, Satoh H, Watanabe Y, Mikami T, Toda K, Okazaki Y, Nabeta K, Hirata K
First Department of Surgery, Sapporo Medical College.
Jpn J Clin Oncol. 1991 Jun;21(3):188-93.
A fiberoptic ductoscopy system was successfully developed by means of which we were able to observe the duct cavity of the breast. Two kinds of silicafiberscopes with outer diameters 0.80 and 0.45 mm were used in the present study. Fiberoptic ductoscopy was applied to 52 ducts in 46 patients with nipple discharge for whom no tumor was palpable; the intraductal appearance could be observed in 47 ducts from 41 patients (90.3%). Fourteen ducts from 13 patients were operated upon and were histologically diagnosed as carcinoma (four cases), intraductal papilloma (nine ducts from eight patients) and mastitis (one case). The internal surface of a normal duct was lustrous and smooth. Cancer growing on the surface of a duct wall appeared white and was slightly elevated, forming a bridging structure. The intraductal papillomas formed intraductal solid nodules, being yellow in most cases and red at the site of hemorrhage. Fiberoptic ductoscopy can be used to recognize the growth of minute intraductal lesions in cases of nipple discharge. Clinical endoscopic diagnosis for minute intraductal lesions will make an important contribution to the early detection of cancer and the evaluation of nipple involvement in intraductal carcinoma.
我们成功研制出一种纤维导管镜检查系统，通过该系统能够观察乳腺导管腔。本研究使用了两种外径分别为0.80毫米和0.45毫米的石英纤维镜。对46例乳头溢液且未触及肿物的患者的52条导管进行了纤维导管镜检查；41例患者的47条导管（90.3%）可观察到导管内表现。对13例患者的14条导管进行了手术，组织学诊断为癌（4例）、导管内乳头状瘤（8例患者的9条导管）和乳腺炎（1例）。正常导管的内表面有光泽且光滑。生长在导管壁表面的癌呈白色，略隆起，形成桥状结构。导管内乳头状瘤形成导管内实性结节，多数情况下呈黄色，出血部位呈红色。纤维导管镜检查可用于识别乳头溢液病例中微小导管内病变的生长情况。对微小导管内病变的临床内镜诊断将对癌症的早期发现以及导管内癌乳头受累情况的评估做出重要贡献。
