Slattum M M, Maggio-Price L, DiGiacomo R F, Russell R G
Department of Comparative Medicine, School of Medicine, University of Washington, Seattle 98195.
Lab Anim Sci. 1991 Apr;41(2):146-50.
During acute cardiopulmonary studies, 33 of 170 (19.4%) dogs developed uncontrollable acidosis accompanied by varying degrees of diarrhea and hypotension. Affected dogs had evidence of gram-negative bacteremia and septic shock. Intravenously administered fluids were contaminated with gram-negative bacteria. Since the experimental procedure entailed nonsurvival surgery, aseptic techniques were not employed. Although aseptic surgical techniques are to be used in animals undergoing survival surgery, such techniques also may be warranted in non-survival surgeries.
在急性心肺研究期间,170只狗中有33只(19.4%)出现了无法控制的酸中毒,并伴有不同程度的腹泻和低血压。受影响的狗有革兰氏阴性菌血症和感染性休克的迹象。静脉输注的液体被革兰氏阴性菌污染。由于实验程序需要进行非存活手术,因此未采用无菌技术。虽然无菌手术技术应用于接受存活手术的动物,但在非存活手术中也可能需要采用此类技术。