Robak J, Kisiel W, Wolbiś M
Department of Pharmacology, N. Copernicus Academy of Medicine, Kraków, Poland.
Pol J Pharmacol Pharm. 1991 Mar-Apr;43(2):145-52.
Ultrasound-induced oxidation of some flavonoids was detected by UV spectral analysis. From among twenty seven compounds investigated only flavonol aglycones and their 7-glycosides, but not 3-glycosides, flavones, catechins and flavanones were found to be oxidized with opening of the ring C. The products of quercetin oxidation were identical with those obtained during slow aerial oxidation of the compound in neutral solution. The oxidation products were deprived of the oxido-reductive properties of native flavonoids. Neither they reduced cytochrome c, nor inhibited lipid oxidation nor scavenged superoxide anions.
通过紫外光谱分析检测到超声诱导的一些黄酮类化合物的氧化。在所研究的27种化合物中，仅发现黄酮醇苷元及其7-糖苷（而非3-糖苷）、黄酮、儿茶素和黄烷酮会发生C环开环氧化。槲皮素氧化产物与该化合物在中性溶液中缓慢空气氧化所得到的产物相同。氧化产物丧失了天然黄酮类化合物的氧化还原特性。它们既不还原细胞色素c，也不抑制脂质氧化，也不清除超氧阴离子。
