两种新的苯并氮杂卓衍生物的合成与药理活性
The synthesis and pharmacological activity of two new derivatives of benzazocine.
作者信息
Gutkowska B, Gumułka S W, Krzaścik P, Poppe I, Mészáros J, Makulska H E
机构信息
Department of Chemical Technology of Drugs, Medical Academy, Warszawa, Poland.
出版信息
Pol J Pharmacol Pharm. 1991 Mar-Apr;43(2):153-63.
PMID:1658757
Abstract
Two new derivatives of benzazocine of anticipated analgesic action were synthesized. Pharmacological investigations were carried out to confirm their analgesic activity, affinity to the opiate receptor and potential antagonistic properties.
摘要
合成了两种预期具有镇痛作用的苯并氮杂卓新衍生物。进行了药理学研究以证实它们的镇痛活性、对阿片受体的亲和力和潜在的拮抗特性。
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