康复的、未服用药物的双相情感障碍患者对强光的褪黑素反应。
Melatonin response to bright light in recovered, drug-free, bipolar patients.
作者信息
Whalley L J, Perini T, Shering A, Bennie J
机构信息
University Dept. of Psychiatry, Western General Hospital, Edinburgh, Scotland, UK.
出版信息
Psychiatry Res. 1991 Jul;38(1):13-9. doi: 10.1016/0165-1781(91)90048-t.
Melatonin suppression by bright light was investigated in 15 drug-free euthymic bipolar patients and control subjects matched for age and sex with the patients. There were no differences between groups on the extent of melatonin suppression by 500 lux bright light administered between 0200h and 0400h. These results do not support the hypothesis that melatonin suppression by bright light is a reliable trait marker in recovered bipolar patients.
在15名未服用药物且处于心境正常状态的双相情感障碍患者以及与这些患者年龄和性别匹配的对照受试者中，研究了强光对褪黑素的抑制作用。在02:00至04:00之间给予500勒克斯的强光，两组在褪黑素抑制程度上没有差异。这些结果不支持强光抑制褪黑素是康复双相情感障碍患者可靠特质标志物的假说。
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