McKay M
Department of Dermatology, Emory University School of Medicine, Atlanta, GA.
Am J Obstet Gynecol. 1991 Oct;165(4 Pt 2):1176-82. doi: 10.1016/s0002-9378(12)90723-1.
Vulvar dermatoses (previously dystrophies) include psoriasis, allergic or irritant reactions, lichen sclerosus, lichen simplex chronicus, lichen planus, and tinea. Some of these have bullous or erosive forms, but they differ from the immune-mediated vesiculobullous disease group, which includes vulvar pemphigus, benign familial pemphigus, pemphigoid, linear IgA disease, and dermatitis herpetiformis. Vulvar ulcers can occur in dermatoses resulting from systemic disease (Behçet's syndrome, lupus, pellagra, and Reiter's disease) or malignancies resembling dermatoses (extramammary Paget's disease, squamous cell carcinoma, and vulvar intraepithelial neoplasia). Many vulvar dermatoses itch or burn. Vulvodynia occurs with irritant and allergic dermatitis, vulvar dermatoses, complications of steroid use, candidiasis, papillomatosis, vestibulitis, or essential (dysesthetic) vulvodynia. Diagnostic tests (potassium hydroxide, cultures, and biopsy) should establish the diagnosis and therapy should be specific. Few skin diseases are curable but all are treatable; effective management is defined by whether a medication reliably controls outbreaks or symptoms when it is used. Patience is recommended, because treatment may take weeks or months.
外阴皮肤病(以前称为营养不良)包括银屑病、过敏或刺激性反应、硬化性苔藓、慢性单纯性苔藓、扁平苔藓和癣。其中一些有大疱性或糜烂性形式,但它们与免疫介导的水疱大疱性疾病组不同,后者包括外阴天疱疮、良性家族性天疱疮、类天疱疮、线状 IgA 病和疱疹样皮炎。外阴溃疡可发生于全身性疾病(白塞病、狼疮、糙皮病和赖特综合征)引起的皮肤病或类似皮肤病的恶性肿瘤(乳房外佩吉特病、鳞状细胞癌和外阴上皮内瘤变)。许多外阴皮肤病会引起瘙痒或灼痛。外阴痛与刺激性和过敏性皮炎、外阴皮肤病、类固醇使用并发症、念珠菌病、乳头瘤病、前庭炎或原发性(感觉异常性)外阴痛有关。诊断性检查(氢氧化钾、培养和活检)应明确诊断,治疗应具有针对性。很少有皮肤病可以治愈,但所有皮肤病都是可治疗的;有效管理的定义是药物使用时是否能可靠地控制发作或症状。建议保持耐心,因为治疗可能需要数周或数月。