Stauffer Laboratory for Physical Chemistry, Stanford University, Stanford, CA 94305.
Proc Natl Acad Sci U S A. 1984 May;81(10):3249-53. doi: 10.1073/pnas.81.10.3249.
Periodic patterns are observed when supported lipid monolayers doped with low concentrations of fluorescent lipid probes are observed with epi-fluorescence microscopy. Monolayers of dipalmitoyl phosphatidylcholine were examined on air-water interfaces and also on alkylated glass coverslips. The patterns are formed by periodic arrays of solid-phase lipid domains in equilibrium with fluid-phase lipid under specified conditions of temperature and two-dimensional lipid pressure. Electrostatic forces may stabilize the periodic ordering of the solid domains.
当用荧光脂质探针低浓度掺杂的支撑脂质单层用荧光显微镜观察时,可以观察到周期性模式。在气-水界面和烷基化玻璃载玻片上检查了二棕榈酰磷脂酰胆碱的单层。这些模式是由在特定温度和二维脂质压力条件下与流体相脂质平衡的固相脂质域的周期性阵列形成的。静电作用力可以稳定固体域的周期性有序。