Dai Y
Zhonghua Yi Xue Za Zhi. 1991 Jul;71(7):366-8, 26.
21 cases of hepatocellular carcinoma (HCC) were surgically resected about 14 or 21 days after transcatheter hepatic arterial chemo-embolization (TACE) mostly for histopathologic assessment of effectiveness. Results showed that complete necrosis of all the tumor bulk was seen in one case (case no. 8) in this series. Partial necrosis of the tumor mass was demonstrated in 19 cases. In 6 cases, the necrotic area was over 50%. In 8 cases, it was between 25-49% and in 5 cases it was below 25%. This strongly indicates a certain effectiveness of TACE on HCC. However, the presence of viable residual tumor in 20 cases, including one with complete viability of the tumor (case no. 1), also suggested the necessity of surgical resection. The case of complete necrosis was related to the frequency of the catheter arriving at the tumor, to the types of embolizing drug, and to the morphopathologic features of the tumor.
21例肝细胞癌（HCC）在经导管肝动脉化疗栓塞术（TACE）后约14或21天接受手术切除，主要用于评估疗效的组织病理学检查。结果显示，本系列中有1例（病例8）肿瘤全部完全坏死。19例显示肿瘤部分坏死。6例坏死面积超过50%。8例坏死面积在25%-49%之间，5例坏死面积低于25%。这有力地表明TACE对HCC有一定疗效。然而，20例存在存活的残留肿瘤，其中1例肿瘤完全存活（病例1），这也提示了手术切除的必要性。完全坏死的病例与导管到达肿瘤的次数、栓塞药物的类型以及肿瘤的形态病理特征有关。
