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[一名接受透析的女性患者的迟发性皮肤卟啉症]

[Porphyria cutanea tarda in a dialyzed female patient].

作者信息

Pérez Lidia, Fernández-Redondo Virginia, Toribio Jaime

机构信息

Servicio de Dermatología, Complejo Hospitalario Universitario, Facultad de Medicina, Santiago de Compostela, Spain.

出版信息

Actas Dermosifiliogr. 2006 Mar;97(2):115-7. doi: 10.1016/s0001-7310(06)73361-0.

Abstract

Dermatological disorders are a frequent finding in patients with renal insufficiency. Porphyria cutanea tarda, pseudoporphyria, phototoxicity or concurrent bullous diseases may cause the appearance of lesions with liquid content in patients in dialysis. We describe the case of a female patient in dialysis who developed bullous lesions. The clinical and laboratory findings were initially compatible with the suspicion of pseudoporphyria, but the finding of some frankly elevated levels of porphyrins in serum, urine and feces confirmed the diagnosis of porphyria cutanea tarda. Porphyria cutanea tarda and pseudoporphyria present with common clinical manifestations. However, the levels of porphyrins in plasma, urine and feces in pseudoporphyria are normal or slightly elevated.

摘要

皮肤疾病在肾功能不全患者中很常见。迟发性皮肤卟啉病、假性卟啉病、光毒性或并发大疱性疾病可能导致透析患者出现含液体的皮损。我们描述了一例透析女性患者出现大疱性皮损的病例。临床和实验室检查结果最初与假性卟啉病的怀疑相符,但血清、尿液和粪便中一些卟啉水平明显升高,确诊为迟发性皮肤卟啉病。迟发性皮肤卟啉病和假性卟啉病有共同的临床表现。然而,假性卟啉病患者血浆、尿液和粪便中的卟啉水平正常或略有升高。

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