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妊娠期鹦鹉热所致脓毒症:围产医学中心的多学科诊疗方法——病例报告综述

Sepsis due to gestational psittacosis: A multidisciplinary approach within a perinatological center--review of reported cases.

作者信息

Janssen Mirjam J, van de Wetering Koos, Arabin Birgit

机构信息

Department of Perinatology, Isala Clinics, Zwolle, The Netherlands.

出版信息

Int J Fertil Womens Med. 2006 Jan-Feb;51(1):17-20.

Abstract

Chlamydia psittaci is associated with significant morbidity and mortality during pregnancy, and its rarity can delay early diagnosis and treatment. A farmer's wife presented at 31 weeks with febrile illness and developed signs of septic shock, indicating immediate delivery. The child developed uneventfully. The mother survived after symptomatic mechanical ventilation, including extracorporeal lung assistance, for 11 days due to multi-organ failure. Only two weeks after admission antibody titres against Chlamydia were rising. The placenta demonstrated acute intervillositis and destruction of throphoblastic cells. Retrospectively, the infection was presumed to derive from infected pregnant sheep. Pregnant women should be advised to avoid contact with sheep and their gestational products. Proper history, early recognition and appropriate management is mandatory for survival of both mother and child.

摘要

鹦鹉热衣原体与孕期严重的发病和死亡相关,且因其罕见性可能会延误早期诊断和治疗。一名农民的妻子在孕31周时出现发热性疾病,并出现感染性休克迹象,提示需立即分娩。孩子发育正常。母亲因多器官衰竭,在接受包括体外肺辅助在内的症状性机械通气11天后存活。入院仅两周后,针对衣原体的抗体滴度开始上升。胎盘显示急性绒毛间炎和滋养层细胞破坏。回顾性分析推测感染源自感染的怀孕绵羊。应建议孕妇避免接触绵羊及其妊娠产物。对于母婴存活而言,详细病史、早期识别和恰当处理必不可少。

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