Liu Jiaming, Gao Yuan
Department of Pulmonary and Critical Care Medicine, Shengjing Hospital of China Medical University, Shenyang, China.
Front Med (Lausanne). 2022 Nov 24;9:1040441. doi: 10.3389/fmed.2022.1040441. eCollection 2022.
Psittacosis is a zoonotic disease caused by . Systemic infections are mainly transmitted through the respiratory tract. The most common related disease is human atypical pneumonia, which is a rare pathogen of community-acquired pneumonia. Due to the difficulty of diagnosis, there have been few reports of pneumonia in the past. In recent years, with the widespread application of metagenomic next-generation sequencing (mNGS), the number of reported cases of has increased year by year. However, at present, most hospitals have little understanding of , especially for severe patients, and lack experience in diagnosis and treatment. Herein, we report the case of a 71-year-old woman with severe pneumonia that caused by . This patient was diagnosed through mNGS and was treated with tigecycline successfully. The level of IL-6 in the BALF was significantly increased. We discontinued tigecycline after mNGS of the blood was negative. In this review, we analyzed 53 cases to summarize the etiology, clinical manifestations, diagnosis and treatment strategies of severe pneumonia and hope to raise clinicians' awareness of this disease.
鹦鹉热是一种由……引起的人畜共患病。全身感染主要通过呼吸道传播。最常见的相关疾病是人类非典型肺炎，它是社区获得性肺炎的一种罕见病原体。由于诊断困难，过去关于……肺炎的报道很少。近年来，随着宏基因组下一代测序（mNGS）的广泛应用，……的报告病例数逐年增加。然而，目前大多数医院对……了解甚少，尤其是对重症患者，缺乏诊断和治疗经验。在此，我们报告一例71岁女性因……导致重症肺炎的病例。该患者通过mNGS确诊，并成功接受替加环素治疗。支气管肺泡灌洗液（BALF）中的白细胞介素-6水平显著升高。血液mNGS结果为阴性后，我们停用了替加环素。在本综述中，我们分析了53例病例，以总结重症……肺炎的病因、临床表现、诊断和治疗策略，并希望提高临床医生对该疾病的认识。
