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一名三岁儿童的多微生物性角膜真菌病。

Polymicrobial keratomycosis in a three-year-old child.

作者信息

Parentin Fulvio, Liberali Tatiana, Perissutti Paolo

机构信息

Department of Surgery-Ophthalmology Unit, Institute of Child Health 'BURLO GAROFOLO', Trieste, Italy.

出版信息

Ocul Immunol Inflamm. 2006 Apr;14(2):129-31. doi: 10.1080/09273940500328487.

Abstract

PURPOSE

To describe a previously unreported case of polymicrobial mycotic keratitis caused by an association between Candida lusitaniae, C. parapsilosis, and Geotrichum candidum.

METHODS

A three-year-old child with an antecedent trauma with vegetable matter and a prolonged use of corticosteroid eyedrops developed fungal keratitis.

RESULTS

The isolates of the corneal scraping using Sabaraud dextrose agar grew C. lusitaniae, C. parapsilosis, and G. candidum. After topical 0.2% and systemic fluconazole treatment, the corneal lesion resolved with no recurrence.

CONCLUSIONS

Corneal trauma with vegetables and the indiscriminate use of corticosteroids are important risk factors for mycotic keratitis. A combination of topical 0.2% and systemic fluconazole therapy was effective in the treatment of this mycotic association. This is the first report of fungal keratitis caused by C. lusitaniae and G. candidum.

摘要

目的

描述一例由葡萄牙念珠菌、近平滑念珠菌和白吉利丝孢酵母联合引起的多微生物真菌性角膜炎病例,此前该病例尚未见报道。

方法

一名三岁儿童因先前有植物性物质外伤史且长期使用皮质类固醇眼药水而发生真菌性角膜炎。

结果

使用沙氏葡萄糖琼脂培养基对角膜刮片进行培养,分离出葡萄牙念珠菌、近平滑念珠菌和白吉利丝孢酵母。经局部使用0.2%氟康唑和全身使用氟康唑治疗后,角膜病变消退,未复发。

结论

植物性角膜外伤和皮质类固醇的滥用是真菌性角膜炎的重要危险因素。局部使用0.2%氟康唑与全身使用氟康唑联合治疗对这种真菌联合感染有效。这是由葡萄牙念珠菌和白吉利丝孢酵母引起的真菌性角膜炎的首例报道。

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