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伴有丰富神经纤维网和真性菊形团的胚胎性肿瘤。是一种新的实体瘤还是仅仅是母细胞瘤(原始神经外胚层肿瘤)的变异型?这就是困境所在。

Embryonal tumor with abundant neuropil and true rosettes. A new entity or only variations of a parent neoplasms (PNETs)? This is the dilemma.

作者信息

La Spina M, Pizzolitto S, Skrap M, Nocerino A, Russo G, Di Cataldo A, Perilongo G

机构信息

Division of Hematology/Oncology, Department of Pediatrics, Catania University Hospital, Catania, Sicily, Italy.

出版信息

J Neurooncol. 2006 Jul;78(3):317-20. doi: 10.1007/s11060-005-9105-x. Epub 2006 Apr 6.

Abstract

A rare embryonal brain tumor has been diagnosed in a 4-year-old boy. The mass, located at the pons and mesencephalon, has been histologically classified as an embryonal tumor containing abundant neuropil and true rosettes. After surgical complete removal of the neoplasia, the child received intensive combined chemotherapy and radiotherapy. He is alive and free of disease at 34 months from surgery. Difficulties in histological definition, possible suggestions for treatment proposals are discussed.

摘要

一名4岁男孩被诊断出患有罕见的胚胎性脑肿瘤。该肿块位于脑桥和中脑,经组织学分类为含有丰富神经纤维网和真性菊形团的胚胎性肿瘤。在手术完全切除肿瘤后,该患儿接受了强化联合化疗和放疗。术后34个月,他仍存活且无疾病迹象。文中讨论了组织学定义方面的困难以及治疗方案的可能建议。

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