Marquardt F, Hammel D, Engel H J, Hachmöller R, Luska G
Abteilung für Thorax-Herz-Gefässchirurgie, Klinikum "Links der Weser" Bremen, Senator Wesslingstrasse 1, 28277 Bremen, Germany.
Clin Res Cardiol. 2006 Jan;95(1):48-53. doi: 10.1007/s00392-006-0312-7.
Reverse flow in the internal thoracic artery (ITA) after coronary bypass surgery due to an occlusion or severe stenosis of the subclavian artery is a rare situation. Symptoms can be recurrent and intermittent angina pectoris in the case of a coronary-subclavian steal (CSSS) or-in addition with cerebral symptoms-in the case of a coronary-subclavian-vertebral steal syndrome (CSVSS).
We describe the cases of four patients with recurrent angina pectoris 5, 11, and 14 years as well as directly after coronary bypass surgery with LITA grafts to LAD. In two patients there was the additional aspect of vertebral steal symptoms with dizziness and intermittent drop attacks.
A PTA of the subclavian occlusions in three cases was not feasible, so that three patients were operated on by extrathoracal approach and carotido-subclavian bypass (CSB) in two cases, and local thrombendarteriectomy of the subclavian and vertebral artery (TEA)+ -patchplasty in one case. Patient 4 was treated by PTA and stent placement into the subclavian artery. Antegrade flow in all four LITAs could be achieved resulting in immediate relief from angina pectoris and cerebral symptoms. Patients 1 and 3 showed no further symptoms with equal BP of the upper extremities and anterograde flow in the LITA grafts and vertebral artery at 10-month follow-up. Patient 2 unfortunately died from an unrelated cause (asthmatic state) 4 months after the operation despite an uneventful recovery.
The occurrence of a CSSS or CSVSS after coronary bypass surgery with retrograde flow in the ITA graft (as described in our four patients) is a rare, but potentially hazardous, situation. If the subclavian occlusion is not amenable to endovascular strategies, the extrathoracal approach by CSB or local TEA and patchplasty provides an excellent means with good midterm and long-term results.
冠状动脉搭桥术后,由于锁骨下动脉闭塞或严重狭窄导致胸廓内动脉(ITA)出现逆流是一种罕见情况。在冠状动脉 - 锁骨下动脉窃血(CSSS)时,症状可能为复发性和间歇性心绞痛;而在冠状动脉 - 锁骨下动脉 - 椎动脉窃血综合征(CSVSS)时,除心绞痛外还伴有脑部症状。
我们描述了4例复发性心绞痛患者的病例,发病时间分别为冠状动脉搭桥术后5年、11年、14年以及术后即刻,均采用左内乳动脉(LITA)移植至左前降支(LAD)。其中2例患者还伴有椎动脉窃血症状,表现为头晕和间歇性跌倒发作。
3例患者的锁骨下动脉闭塞行血管腔内血管成形术(PTA)不可行,因此,2例行胸外途径颈动脉 - 锁骨下动脉搭桥术(CSB),1例行锁骨下动脉和椎动脉局部血栓内膜切除术(TEA)及补片成形术。患者4接受了锁骨下动脉PTA及支架置入术。所有4例患者的LITA均实现了顺行血流,心绞痛和脑部症状立即缓解。患者1和3在10个月随访时,上肢血压相等,LITA移植物和椎动脉顺行血流,未出现进一步症状。患者2不幸在术后4个月因无关原因(哮喘状态)死亡,尽管术后恢复过程平稳。
冠状动脉搭桥术后出现ITA移植物逆流的CSSS或CSVSS情况(如我们的4例患者所述)罕见,但具有潜在危险性。如果锁骨下动脉闭塞不适于血管内治疗策略,胸外CSB或局部TEA及补片成形术是一种中期和长期效果良好的极佳治疗方法。