Zhou Ji-Chang, Huang Cheng-Yu, Zhang Hui-Min, Liu Xiao-Li, Yang Xiaoguang, Pu Jianhua, Jia Qing, Hong Junrong
Department of Nutrition and Food Hygiene, West China School of Public Health, Sichuan University, Chengdu 610041, China.
Wei Sheng Yan Jiu. 2006 Jan;35(1):66-8.
The study was aimed to evaluate the iron absorption in the Tibetan man's diet using the stable isotopic iron, and present a reference to improve the dietary iron absorption for Chinese.
In the study conducted on the spot of high altitude (> 3500m), the iron tracer (FeSO4 enriched with 57Fe) and the recovery indicator dysprosium (Dy) were orally administrated to 16 young Tibetan men, and their feces were sampled. The ratios of 57Fe/56Fe in fecal samples was determined by inductively coupled plasma mass spectrometry, and then the iron absorption was calculated based on the principle of isotope dilution.
The rate of dietary iron absorption in young Tibetan men was 13.4% +/- 6.4% with good linear correlation between daily fecal excretions of iron tracer and Dy.
Dy had the same behavior as non-absorbed iron tracer in the digestive tract and the recovery of Dy may indicate the completeness of fecal collection. Dietary iron absorption in the adult Tibetan man was relatively high.
本研究旨在利用稳定同位素铁评估藏族男性饮食中铁的吸收情况，并为改善中国人饮食中铁的吸收提供参考。
在海拔>3500米的现场进行研究，给16名年轻藏族男性口服铁示踪剂（富含57Fe的FeSO4）和回收指示剂镝（Dy），并采集他们的粪便。通过电感耦合等离子体质谱法测定粪便样本中57Fe/56Fe的比值，然后根据同位素稀释原理计算铁的吸收量。
年轻藏族男性饮食中铁的吸收率为13.4%±6.4%，铁示踪剂的每日粪便排泄量与Dy之间存在良好的线性相关性。
Dy在消化道中的行为与未吸收的铁示踪剂相同，Dy的回收率可能表明粪便收集的完整性。成年藏族男性饮食中铁的吸收相对较高。
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