Lin W L, Deng J F, Chou L J, Hung D Z, Tsai W J
Department of Medicine, Veterans General Hospital-Taipei.
Zhonghua Yi Xue Za Zhi (Taipei). 1991 Oct;48(4):305-9.
Amphetamines abuse has recently become a problem in this country. Four case identification, we used Emit-d.a.u. amphetamine assay to screen the amphetamines in human urine, and then confirmed them by gas chromatography-ion trap detector (GC-ITD). From January 1989 to August 1990, 267 urinary samples were requested by the physicians for amphetamine identification. Six samples were accompanied with drug powders used by the patients. Among the 267 samples, 79 were confirmed for the presence for both of methamphetamine and amphetamine. Neither the presence of amphetamine nor methamphetamine itself was detected. Among the six packs of drug powder tested, methamphetamine but not amphetamine was detected in four. We found that fenfluramine and diethylpropion would have false positive amphetamine reactions in Emit-d.a.u. assay. All the samples originated from 34 hospitals were widely distributed in the country. Other drugs concomitantly used included ethanol, morphine, flunitrazepam and ephedrine. Since methamphetamine can be metabolized to amphetamine but not vers versa, our study confirmed the abuse of methamphetamine not amphetamine in this country.
苯丙胺滥用最近在该国已成为一个问题。为进行病例鉴定，我们使用Emit-d.a.u.苯丙胺检测法对人尿液中的苯丙胺进行筛查，然后通过气相色谱-离子阱检测器（GC-ITD）进行确认。从1989年1月至1990年8月，医生共送检267份尿液样本用于苯丙胺鉴定。其中6份样本伴有患者使用的药粉。在这267份样本中，79份被确认为同时含有甲基苯丙胺和苯丙胺。未检测到苯丙胺或甲基苯丙胺本身。在所检测的6包药粉中，有4包检测出甲基苯丙胺但未检测出苯丙胺。我们发现芬氟拉明和二乙丙胺在Emit-d.a.u.检测法中会出现苯丙胺假阳性反应。所有来自34家医院的样本在该国分布广泛。同时使用的其他药物包括乙醇、吗啡、氟硝西泮和麻黄碱。由于甲基苯丙胺可代谢为苯丙胺，反之则不然，我们的研究证实该国存在甲基苯丙胺滥用而非苯丙胺滥用情况。
