Tsai Meng-Han, Tsai Nai-Wen, Chen Shu-Fang, Tsai Hui-Hong, Lu Cheng-Hsien, Huang Chi-Ren, Chang Wen-Neng
Department of Neurology, Chang Gung Memorial Hospital-Kaohsiung, Kaohsiung, Taiwan.
Acta Neurol Taiwan. 2006 Mar;15(1):34-7.
The neurologic manifestations of organophosphate intoxication are many, and different pathophysiologic mechanisms are responsible for the different presentations occurring at different stages of the disease process. Movement disorders constitute one of the neurologic manifestations, which may include Parkinsonism or other dyskinetic movements. However, involuntary coital-like movements have not been reported as one of the organophosphate intoxication-related movement disorders. In this case report, we describe a 71-year-old man who developed involuntary coital-like movements about one and a half months after an event of organophosphate intoxication in an attempt to commit suicide. The involuntary movements were to-and-fro pelvic thrusting and back-rocking movements. The patient was able to suppress the involuntary movements for a short period of time, although they usually persisted all day long. The involuntary movements occurred in all postures including standing, sitting and in supine postures, resulting in great embarrassment. These involuntary movements also interfered with the initiation of sleep, although they discontinued while asleep. With clonazepam and piracetam therapy, the involuntary coital-like movements of this patient decreased in amplitude, although remaining to a degree even after one year of follow-up.
有机磷中毒的神经系统表现多种多样，不同的病理生理机制导致疾病过程不同阶段出现不同表现。运动障碍是神经系统表现之一，可能包括帕金森症或其他运动障碍。然而，类似性交的不自主运动尚未被报道为与有机磷中毒相关的运动障碍之一。在本病例报告中，我们描述了一名71岁男性，在一次有机磷中毒自杀事件发生约一个半月后出现了类似性交的不自主运动。不自主运动为骨盆前后推挤和身体后摇动作。患者能够在短时间内抑制不自主运动，尽管它们通常整日持续。不自主运动在包括站立、坐着和仰卧等所有姿势下都会出现，造成极大尴尬。这些不自主运动也干扰了睡眠起始，尽管在睡眠时会停止。经过氯硝西泮和吡拉西坦治疗，该患者类似性交的不自主运动幅度减小，尽管在随访一年后仍有一定程度存在。
