Kohl Thomas, Gembruch Ulrich, Filsinger Barbara, Hering Rudolf, Bruhn Jorgen, Tchatcheva Kristina, Aryee Sebastian, Franz Axel, Heep Axel, Muller Andreas, Bartmann Peter, Loff Stefan, Hosie Stuart, Neff Wolfgang, Schaible Thomas
German Center for Fetal Surgery and Minimally Invasive Therapy, University Hospital of Bonn, Germany.
Fetal Diagn Ther. 2006;21(3):314-8. doi: 10.1159/000091363.
In order to assess the effect of deliberately delayed percutaneous fetoscopic tracheal occlusion on survival of fetuses with life-threatening congenital diaphragmatic hernia.
Eight fetuses with life-threatening congenital diaphragmatic hernia underwent fetoscopic tracheal balloon occlusion between 29 + 0 and 32 + 4 weeks of gestation. Delayed occlusion was chosen in order to minimize potentially negative pulmonary effects from premature delivery as a result of fetal surgery. In addition, we wanted to become able to provide all available postnatal intensive care treatment means in these patients.
Six of the 8 fetuses survived to discharge from hospital.
Delayed fetoscopic tracheal balloon occlusion may be rewarded with lung growth sufficient to allow survival of fetuses with life-threatening congenital diaphragmatic hernia.
评估故意延迟经皮胎儿镜气管闭塞术对患有危及生命的先天性膈疝胎儿存活率的影响。
8例患有危及生命的先天性膈疝的胎儿在妊娠29 + 0至32 + 4周期间接受了胎儿镜气管球囊闭塞术。选择延迟闭塞是为了尽量减少因胎儿手术导致早产而产生的潜在负面肺部影响。此外，我们希望能够为这些患者提供所有可用的产后重症监护治疗手段。
8例胎儿中有6例存活至出院。
延迟胎儿镜气管球囊闭塞术可能会使肺部充分生长，从而使患有危及生命的先天性膈疝的胎儿存活。
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