鼓励开展早期临床经验，采用故意延迟的临时胎儿镜气管闭塞术对危及生命的左右先天性膈疝进行产前治疗。
Encouraging early clinical experience with deliberately delayed temporary fetoscopic tracheal occlusion for the prenatal treatment of life-threatening right and left congenital diaphragmatic hernias.
作者信息
Kohl Thomas, Gembruch Ulrich, Filsinger Barbara, Hering Rudolf, Bruhn Jorgen, Tchatcheva Kristina, Aryee Sebastian, Franz Axel, Heep Axel, Muller Andreas, Bartmann Peter, Loff Stefan, Hosie Stuart, Neff Wolfgang, Schaible Thomas
机构信息
German Center for Fetal Surgery and Minimally Invasive Therapy, University Hospital of Bonn, Germany.
出版信息
Fetal Diagn Ther. 2006;21(3):314-8. doi: 10.1159/000091363.
OBJECTIVE
In order to assess the effect of deliberately delayed percutaneous fetoscopic tracheal occlusion on survival of fetuses with life-threatening congenital diaphragmatic hernia.
METHODS
Eight fetuses with life-threatening congenital diaphragmatic hernia underwent fetoscopic tracheal balloon occlusion between 29 + 0 and 32 + 4 weeks of gestation. Delayed occlusion was chosen in order to minimize potentially negative pulmonary effects from premature delivery as a result of fetal surgery. In addition, we wanted to become able to provide all available postnatal intensive care treatment means in these patients.
RESULTS
Six of the 8 fetuses survived to discharge from hospital.
CONCLUSION
Delayed fetoscopic tracheal balloon occlusion may be rewarded with lung growth sufficient to allow survival of fetuses with life-threatening congenital diaphragmatic hernia.
目的
评估故意延迟经皮胎儿镜气管闭塞术对患有危及生命的先天性膈疝胎儿存活率的影响。
方法
8例患有危及生命的先天性膈疝的胎儿在妊娠29 + 0至32 + 4周期间接受了胎儿镜气管球囊闭塞术。选择延迟闭塞是为了尽量减少因胎儿手术导致早产而产生的潜在负面肺部影响。此外，我们希望能够为这些患者提供所有可用的产后重症监护治疗手段。
结果
8例胎儿中有6例存活至出院。
结论
延迟胎儿镜气管球囊闭塞术可能会使肺部充分生长，从而使患有危及生命的先天性膈疝的胎儿存活。
Zotero 插件