Frommelt Peter C
Division of Pediatric Cardiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Curr Opin Cardiol. 2006 May;21(3):194-9. doi: 10.1097/01.hco.0000221580.63996.93.
The past year has seen a continued evolution in the echocardiographic assessment of diastolic function in children. This paper reviews published studies from the past year that have helped characterize diastolic function using echocardiography in children.
Characterization of diastolic function using Doppler and Doppler tissue imaging in the normal infant and child was a primary focus of pediatric echocardiographic investigation. These technologies appear to hold significant promise as tools to improve understanding of diastolic function in the normal child as the heart matures. Diastolic function in children with congenital heart disease has also been better characterized using these tools, specifically in patients with atrial septal defects, tetralogy of Fallot, single ventricle physiology, and following cardiac transplantation. Finally, diastolic function in acquired heart disease or with systemic disease in the child has been evaluated using echocardiography, with recent reports describing findings in children with dilated cardiomyopathy, chronic renal disease, obesity, type I diabetes, juvenile rheumatoid arthritis, obstructive sleep apnea, and after anthracycline exposure for childhood cancer.
Pediatric echocardiography has clearly become the primary tool for describing and characterizing diastolic function in infants and children both with and without heart disease. It is becoming an important noninvasive diastolic monitoring tool that allows serial assessment of pathologic diastolic disease in both primary myocardial and systemic disease states.
过去一年,儿童舒张功能的超声心动图评估持续发展。本文回顾过去一年发表的研究,这些研究有助于利用超声心动图对儿童舒张功能进行特征描述。
使用多普勒和多普勒组织成像对正常婴幼儿舒张功能进行特征描述是儿科超声心动图研究的主要重点。随着心脏成熟,这些技术作为增进对正常儿童舒张功能理解的工具似乎具有重大前景。利用这些工具,先天性心脏病患儿的舒张功能也得到了更好的特征描述,特别是房间隔缺损、法洛四联症、单心室生理状态患儿以及心脏移植术后患儿。最后,已利用超声心动图对儿童获得性心脏病或全身性疾病的舒张功能进行了评估,最近的报告描述了扩张型心肌病、慢性肾病、肥胖、1型糖尿病、幼年类风湿关节炎、阻塞性睡眠呼吸暂停患儿以及儿童癌症接受蒽环类药物治疗后的舒张功能研究结果。
儿科超声心动图显然已成为描述和特征化患有和未患有心脏病的婴幼儿舒张功能的主要工具。它正成为一种重要的无创舒张功能监测工具,可对原发性心肌疾病和全身性疾病状态下的病理性舒张功能障碍进行系列评估。