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巩膜补片移植的结构和功能结果。

Structural and functional outcome of scleral patch graft.

作者信息

Sangwan V S, Jain V, Gupta P

机构信息

LV Prasad Eye Institute, Banjara Hills, Hyderabad, Andhra Pradesh, India.

出版信息

Eye (Lond). 2007 Jul;21(7):930-5. doi: 10.1038/sj.eye.6702344. Epub 2006 Apr 7.

Abstract

PURPOSE

To evaluate the visual and structural outcomes of scleral patch grafting in cases of scleral defect.

METHODS

The study was a retrospective interventional case series. Medical records of all patients who underwent scleral patch grafting at a tertiary care centre between 1997 and 2003 for scleral defects were reviewed. After removal of all the devitalized tissue, alcohol-preserved full-thickness sclera was tailored to fit the defect and sutured in place. The graft was covered with a conjunctival flap or amniotic membrane. Structural integrity and visual outcome were assessed as the main outcome measures.

RESULTS

A total of 13 eyes of 13 patients required scleral patch grafting for scleral defects of varying aetiologies, the most common being necrotizing scleritis following pterygium surgery (40%). The patients were followed up for 6-60 months, an average period of 24.3 months. Tectonic success was achieved in 10 eyes (76.9%). Three complications were noted: endophthalmitis, graft necrosis, and graft dehiscence with uveal prolapse. However, no regrafts were needed. Epithelialization and vascularization were seen in the remaining eyes after an average duration of 3-4 weeks. Visual acuity remained stable in the majority (9/13, 60%), improved in one and deteriorated in three eyes.

CONCLUSIONS

Scleral grafting with overlying conjunctival or amniotic membrane graft is an effective and simple measure for preserving globe integrity both structurally and functionally.

摘要

目的

评估巩膜缺损病例中巩膜补片移植的视觉和结构结果。

方法

本研究为回顾性干预病例系列。回顾了1997年至2003年在一家三级医疗中心因巩膜缺损接受巩膜补片移植的所有患者的病历。去除所有失活组织后,将酒精保存的全层巩膜裁剪以适合缺损处并缝合到位。移植物用结膜瓣或羊膜覆盖。将结构完整性和视觉结果作为主要结局指标进行评估。

结果

13例患者的13只眼因不同病因的巩膜缺损需要进行巩膜补片移植,最常见的病因是翼状胬肉手术后的坏死性巩膜炎(40%)。患者随访6 - 60个月,平均24.3个月。10只眼(76.9%)实现了结构成功。记录到3种并发症:眼内炎、移植物坏死和伴有葡萄膜脱垂的移植物裂开。然而,无需再次移植。其余眼睛在平均3 - 4周后出现上皮化和血管化。大多数患者(9/13,60%)视力保持稳定,1只眼视力改善,3只眼视力下降。

结论

巩膜移植联合覆盖结膜或羊膜移植是在结构和功能上保持眼球完整性的一种有效且简单的措施。

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