Yahia Rabha Ben, Lichnovská Radka, Brychta Tomás
Institute of Physiology, Palacký University, 775 15 Olomouc, Czech Republic.
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2005 Dec;149(2):237-41.
Peroxisome proliferator-activated receptors (PPARs) are subgroups of nuclear hormonal receptors of transcripting factors mostly found in adipose tissue. They are described as important regulators of lipid and saccharide metabolism including insulin sensitivity; therefore they are taken as marker of metabolic syndrome. Their synthetic ligands could be used as drugs for insulin resistance and type 2 diabetes mellitus.
过氧化物酶体增殖物激活受体（PPARs）是转录因子核激素受体的亚组，主要存在于脂肪组织中。它们被认为是脂质和糖类代谢的重要调节因子，包括胰岛素敏感性；因此，它们被视为代谢综合征的标志物。其合成配体可作为治疗胰岛素抵抗和2型糖尿病的药物。
