Mehallo Christopher J, Drezner Jonathan A, Bytomski Jeffrey R
McShane Sports Medicine, 1098 West Baltimore Pike, Suite 3308, Media, PA 19063, and Department of Family Medicine, Hall Health Center Sports Medicine, University of Washington, Box 354775, Seattle, WA 98105, USA.
Clin J Sport Med. 2006 Mar;16(2):170-4. doi: 10.1097/00042752-200603000-00015.
Nonsteroidal antiinflammatory drugs (NSAIDs) are frequently used in the treatment of acute athletic injuries, often for analgesic purposes as the evidence to support enhanced healing is limited. However, the current evidence on NSAID use in athletic injury is slowly growing. On the basis of animal models and limited human studies, some practical management guidelines can be drawn to assist the sports physician. Specifically, NSAIDs are not recommended in the treatment of completed fractures, stress fractures at higher risk of nonunion, or in the setting of chronic muscle injury. The only exception may be very short-term use (eg, a few days) for analgesic purposes only. Judicious use of NSAIDs may be more appropriate in the management of acute ligament sprains, muscle strains, tendinitis, and eccentric muscle injury. However, length of treatment should always be kept as short as possible, with consideration of the specific type of injury, level of dysfunction, and pain.
非甾体抗炎药（NSAIDs）常用于治疗急性运动损伤，通常用于止痛，因为支持促进愈合的证据有限。然而，目前关于NSAIDs在运动损伤中应用的证据正在缓慢增加。基于动物模型和有限的人体研究，可以得出一些实用的管理指南来协助运动医学医生。具体而言，不建议在治疗完全骨折、骨不连风险较高的应力性骨折或慢性肌肉损伤时使用NSAIDs。唯一的例外可能是仅用于止痛目的的非常短期使用（例如，几天）。在急性韧带扭伤、肌肉拉伤、肌腱炎和离心性肌肉损伤的管理中，谨慎使用NSAIDs可能更合适。然而，治疗时间应始终尽可能缩短，并考虑损伤的具体类型、功能障碍程度和疼痛情况。
