Kułakowski A, Dardziński R
Department of Surgical Oncology, Maria Skłodowska-Curie Memorial Cancer Centre and Institute of Oncology, Warsaw, Poland.
Eur J Surg Oncol. 1991 Dec;17(6):581-4.
Twelve years of experience in performing retroperitoneal lymph node dissection (RPLND) in patients with testicular non-seminomas is presented. One hundred and fifty-two procedures were performed during the years 1977-1989. Seventy-four patients had RPLND prior to chemotherapy and 78 were operated on after the initial chemotherapy. The disparity between the initial staging and intra-operative findings was 35% in the first group and 16% in the second. The mortality rate in both groups was similar (20.3% and 20.5%, respectively). Forty-one of 78 patients operated on after the initial chemotherapy had vital or only partially damaged neoplastic tissue found in the specimen. The diagnostic and therapeutic significance of RPLND is discussed and the importance of the pathological findings in planning postoperative chemotherapy, and in prognosis is stressed.
本文介绍了对睾丸非精原细胞瘤患者进行腹膜后淋巴结清扫术(RPLND)的12年经验。1977年至1989年期间共进行了152例手术。74例患者在化疗前接受了RPLND,78例在初始化疗后接受了手术。第一组初始分期与术中发现的差异为35%,第二组为16%。两组的死亡率相似(分别为20.3%和20.5%)。78例在初始化疗后接受手术的患者中,有41例在标本中发现有存活或仅部分受损的肿瘤组织。讨论了RPLND的诊断和治疗意义,并强调了病理结果在规划术后化疗和预后方面的重要性。